{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T16:24:09Z","timestamp":1787675049598,"version":"build-2784847793"},"reference-count":30,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T00:00:00Z","timestamp":1779840000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T00:00:00Z","timestamp":1779840000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["arthroscopyjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthroscopy"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To investigate whether prophylactic use of low\u2010molecular\u2010weight heparin (enoxaparin) after knee arthroscopy reduces the incidence of symptomatic venous thromboembolism (VTE) compared with no postoperative pharmacological prophylaxis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a population\u2010based cohort study using linked national insurance and hospital data from January 1, 2016, to December 31, 2023. Adults undergoing standard knee arthroscopy were identified and included, and those with prior VTE, coagulation disorders, recent cancer, preoperative anticoagulation, septic arthritis, or extended hospital stay were excluded. Patients filling a prophylactic enoxaparin prescription within 5\u2009days of discharge comprised the enoxaparin group; all others formed the control group. The primary outcome was symptomatic VTE (combined deep vein thrombosis and pulmonary embolism) within 90\u2009days after group allocation. Secondary safety outcomes included wound infection, septic arthritis, heparin\u2010induced thrombocytopenia, intracranial hemorrhage, gastrointestinal bleeding, epistaxis, and surgery\u2010related bleeding leading to hospitalization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 181,135 knee arthroscopies identified, 99,916 patients met the inclusion criteria. Among them, 67,108 (67%) received enoxaparin and 32,808 (33%) did not. Symptomatic VTE occurred in 380 patients (0.57%) in the enoxaparin group and 293 patients (0.89%) in the control group. Enoxaparin prophylaxis was associated with a significantly lower incidence of symptomatic VTE (hazard ratio: 0.64; 95% confidence interval: 0.55\u20100.74;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.0003), corresponding to a number needed to treat of 310 to prevent 1 symptomatic event. Adverse events were rare in both groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Prophylactic enoxaparin after knee arthroscopy was associated with a significantly reduced risk of symptomatic VTE within 95\u2009days of discharge compared with\u00a0no pharmacological prophylaxis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level III, retrospective comparative case series.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/arj.70341","type":"journal-article","created":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T09:57:51Z","timestamp":1779875871000},"page":"1764-1774","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prophylactic Enoxaparin Reduces Symptomatic Venous Thromboembolism Compared With No Chemoprophylaxis Within 95\u2009Days After Knee Arthroscopy"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1432-7269","authenticated-orcid":false,"given":"Aylin","family":"Albrecht","sequence":"first","affiliation":[{"name":"Department of Anaesthesia, Intensive Care Medicine and Pain Medicine, Clinical Division of General Anaesthesia and Intensive Care Medicine Medical University of Vienna  Vienna Austria"},{"name":"Ludwig Boltzmann Institute Digital Health and Patient Safety  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3316-9024","authenticated-orcid":false,"given":"Lorenz","family":"Kapral","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Intensive Care Medicine and Pain Medicine, Clinical Division of General Anaesthesia and Intensive Care Medicine Medical University of Vienna  Vienna Austria"},{"name":"Ludwig Boltzmann Institute Digital Health and Patient Safety  Vienna Austria"},{"name":"Department of Informatics, Research Unit Machine Learning Technical University Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Gruber","sequence":"additional","affiliation":[{"name":"Federation of Social Insurance  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2270-0089","authenticated-orcid":false,"given":"Christoph","family":"Dibiasi","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Intensive Care Medicine and Pain Medicine, Clinical Division of General Anaesthesia and Intensive Care Medicine Medical University of Vienna  Vienna Austria"},{"name":"Ludwig Boltzmann Institute Digital Health and Patient Safety  Vienna 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