{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T14:01:44Z","timestamp":1790085704336,"version":"4.0.1"},"reference-count":36,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:00:00Z","timestamp":1790035200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:00:00Z","timestamp":1790035200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["arthroscopyjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthroscopy"],"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To define clinically meaningful outcomes after hip arthroscopy (HA) with periacetabular osteotomy (PAO), HA\u2009+\u2009PAO in patients with Ehlers\u2010Danlos syndrome (EDS) using the Patient\u2010Reported Outcomes Measurement Information System (PROMIS) and International Hip Outcome Tool 12 (iHOT\u201012) and compare these with a non\u2010EDS cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Prospectively collected data from patients undergoing HA\u2009+\u2009PAO between 2018 and 2023 at tertiary hip preservation centers with dedicated referral populations for EDS were retrospectively analyzed. Patients with hip dysplasia or instability and \u22652\u2010year follow\u2010up were included. All patients in the EDS cohort had been diagnosed by an outside provider with either a nongenetic or genetic subtype of EDS. The non\u2010EDS group was constructed as a comparison cohort selected to approximate the EDS group. Outcome measures included iHOT\u201012 and PROMIS computer adaptive tests: Physical Function (PF), Global Physical Health, Global Mental Health, and Pain Interference. Minimal Clinically Important Difference, Patient Acceptable Symptom State (PASS), and Maximal Outcome Improvement were calculated for these measures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The non\u2010EDS cohort included 103 patients, and the EDS cohort included 26. The mean\u2009\u00b1\u2009standard deviation age was 25.1\u2009\u00b1\u20094.2 and 28.7\u2009\u00b1\u20096.2 (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.01) for the non\u2010EDS and EDS groups, respectively. Both groups reported &gt;80% satisfaction at 1 and 2\u2009years. Minimal Clinically Important Difference values for the iHOT\u201012, PROMIS\u2010PF, and PROMIS\u2010Depression in the non\u2010EDS cohort were 13.7, 4.4, and 4.4 at 1\u2009year and 11.2, 3.5, and 4.6 at 2\u2009years, respectively. Minimal Clinically Important Difference agreement analysis was comparable between groups. However, EDS patients showed lower absolute PASS and Maximal Outcome Improvement agreement, particularly for PROMIS\u2010PF, with 43% of EDS patients achieving 1\u2010year absolute PASS compared with 78% of non\u2010EDS patients. PROMIS\u2010Depression outcomes showed a higher absolute PASS agreement in EDS patients with 87% achieving this outcome compared with 57.5% in the non\u2010EDS cohort.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Patients with EDS undergoing HA\u2009+\u2009PAO achieve significant improvements in function, pain, and mental health, as measured by iHOT\u201012, PROMIS\u2010PF, and PROMIS\u2010Pain Interference. Despite lower PROMIS\u2010PF gains compared with non\u2010EDS patients, satisfaction and clinically meaningful outcomes are comparable.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level III, comparative retrospective study.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/arj.70608","type":"journal-article","created":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T13:15:58Z","timestamp":1790082958000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Ehlers\u2010Danlos Patients Achieve High Satisfaction and Clinically Meaningful Outcomes After Combined Hip Arthroscopy and Periacetabular Osteotomy: A Comparative Study With Non\u2010Ehlers\u2010Danlos Syndrome 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