{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:47:20Z","timestamp":1761630440834},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,11,22]],"date-time":"2005-11-22T00:00:00Z","timestamp":1132617600000},"content-version":"vor","delay-in-days":12563,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis &amp; Rheumatism"],"published-print":{"date-parts":[[1971,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Twelve of 23 patients with dermatomyositis or polymyositis demonstrated myoglobin in their serum or urine in concentrations of 0.005\u20133.280 mg\/ml. This was detected by means of a specific immunologic assay. Myoglobin was more frequently noted in serum than urine. The frequency of appearance of myoglobin in these patients was not related to age or sex, but was more common among those with dermatomyositis (11 of 18) than polymyositis (1 of 5). Serum enzyme values (SGOT, CPK, LDH) were slightly higher in the group with myoglobinemia than in those without, but there was considerable overlap. Myoglobin was found in most patients with myositis before steroid therapy was begun (12 of 19), and its presence was associated with renal failure in two patients.<\/jats:p>","DOI":"10.1002\/art.1780140405","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T16:02:51Z","timestamp":1171468971000},"page":"457-464","source":"Crossref","is-referenced-by-count":34,"title":["Myoglobinemia and myoglobinuria in patients with myositis"],"prefix":"10.1002","volume":"14","author":[{"given":"Lawrence J.","family":"Kagen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,22]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/9.2.206"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/15.8.436"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.34.1.398"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/2191174a0"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1964.00460180003001"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/path.1700540113"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1113\/expphysiol.1944.sp000896"},{"key":"e_1_2_1_9_2","first-page":"440","article-title":"Uraemia in the rabbit after injection of crystalline myoglobin","volume":"33","author":"Perri GC","year":"1952","journal-title":"Brit J Exp Path"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-67-6-1183"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(70)90017-3"},{"key":"e_1_2_1_12_2","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1152\/ajplegacy.1966.211.3.656","article-title":"Immunologic measurements of myoglobin in human adult and fetal skeletal muscle","volume":"211","author":"Kagen LJ","year":"1966","journal-title":"Amer J Physiol"},{"key":"e_1_2_1_13_2","first-page":"667","article-title":"Precipitin reactions of anti\u2010human myoglobin serum with several human and animal muscle extracts","volume":"12","author":"Kagen LJ","year":"1967","journal-title":"Immunology"},{"key":"e_1_2_1_14_2","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1152\/ajplegacy.1926.78.3.675","article-title":"Muscle hemoglobin as a source of bile pigment","volume":"78","author":"Whipple GH","year":"1926","journal-title":"Amer J Physiol"},{"key":"e_1_2_1_15_2","first-page":"277","article-title":"Experimental investigation of the metabolism of myoglobin","volume":"14","author":"Amako T","year":"1963","journal-title":"Kyushu J Med Sci"},{"key":"e_1_2_1_16_2","unstructured":"BywatersEGL:The Muscle. Paris L'Expansion 1952 pp213\u2013228"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-130-33688"},{"key":"e_1_2_1_18_2","first-page":"269","article-title":"Polymyositis and dermatomyositis","volume":"12","author":"Pearson CM","year":"1962","journal-title":"Bull Rheum Dis"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01894044"},{"key":"e_1_2_1_20_2","first-page":"531","article-title":"\u00dcber einen Fall von paralytischer H\u00e4moglobinurie beim Menschen","volume":"7","author":"Paul F","year":"1924","journal-title":"Wien Arch Inn Med"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1115411"},{"key":"e_1_2_1_22_2","first-page":"1071","article-title":"Polimiosite mioglobinurica","volume":"44","author":"Nardini A","year":"1963","journal-title":"Giorn Clin Med"},{"key":"e_1_2_1_23_2","volume-title":"Polymyositis","author":"Walton JN","year":"1958"}],"container-title":["Arthritis &amp; Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fart.1780140405","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/art.1780140405","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T14:21:16Z","timestamp":1700749276000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/art.1780140405"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1971,7]]},"references-count":22,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1971,7]]}},"alternative-id":["10.1002\/art.1780140405"],"URL":"https:\/\/doi.org\/10.1002\/art.1780140405","archive":["Portico"],"relation":{},"ISSN":["0004-3591","1529-0131"],"issn-type":[{"value":"0004-3591","type":"print"},{"value":"1529-0131","type":"electronic"}],"subject":[],"published":{"date-parts":[[1971,7]]}}}