{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T19:55:19Z","timestamp":1759694119856},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,11,22]],"date-time":"2005-11-22T00:00:00Z","timestamp":1132617600000},"content-version":"vor","delay-in-days":11893,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis &amp; Rheumatism"],"published-print":{"date-parts":[[1973,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Marrow granulocyte reserves, as measured by the administration of etiocholanolone, were studied in 59 patients with a variety of rheumatic diseases. The majority of patients with systemic lupus erythematosus (62%) and all patients with chronic hepatitis and Felty's syndrome tested had abnormally low granulocyte reserves. Patients with rheumatoid arthritis and Sj\u00f6gren's syndrome were generally normal. No correlation could be established between deficient bone marrow responses and other clinical or laboratory parameters such as leukopenia. Plasma was obtained in 2 patients when they exhibited diminished marrow reserves. After treatment of these patients and a return of the etiocholanolone test to normal, reinfusion of the plasma had a suppressive effect on the marrow reserve, suggesting that a humoral factors) may be responsible for the abnormality.<\/jats:p>","DOI":"10.1002\/art.1780160308","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T16:21:05Z","timestamp":1171470065000},"page":"345-352","source":"Crossref","is-referenced-by-count":29,"title":["Marrow Granulocyte Reserves in the Rheumatic Diseases"],"prefix":"10.1002","volume":"16","author":[{"given":"Harry R.","family":"Kimball","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheldon M.","family":"Wolff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norman","family":"Talal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul H.","family":"Plotz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John L.","family":"Decker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,22]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1182\/blood.V6.11.1059.1059","article-title":"The hematologic aspects of disseminated (systemic) lupus erythematosus.","volume":"6","author":"Michael SR","year":"1951","journal-title":"Blood"},{"key":"e_1_2_1_3_2","first-page":"219","volume-title":"Arthritis.","author":"Hollander JE","year":"1966"},{"key":"e_1_2_1_4_2","first-page":"1158","volume-title":"Clinical Hematology.","author":"Wintrobe MM","year":"1967"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-67-6-1226"},{"key":"e_1_2_1_6_2","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1182\/blood.V31.5.580.580","article-title":"Correlation of granulocyte mobilization with etiocholanolone and the subsequent development of myelosuppression in patients with acute leukemia receiving therapy.","volume":"31","author":"Godwin HA","year":"1968","journal-title":"Blood"},{"key":"e_1_2_1_7_2","first-page":"643","article-title":"Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association: Preliminary criteria for the classification of systemic lupus erythematosus.","volume":"21","year":"1971","journal-title":"Bull Rheum Dis"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(195902)2:1<16::AID-ART1780020104>3.0.CO;2-9"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-196505000-00001"},{"key":"e_1_2_1_10_2","first-page":"415","article-title":"Quantative aspects of pyrogenic and hematologic responses to etiocholanolone in man.","volume":"69","author":"Kimball HR","year":"1967","journal-title":"J Lab Clin Med"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/53.5.647"},{"key":"e_1_2_1_12_2","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1182\/blood.V30.4.474.474","article-title":"The effect of etiocholanolone on granulocyte kinetics.","volume":"30","author":"Vogel JM","year":"1967","journal-title":"Blood"},{"key":"e_1_2_1_13_2","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1182\/blood.V31.4.461.461","article-title":"The effect of etiocholanolone on the entry of granulocytes into the peripheral blood.","volume":"31","author":"Goodwin HR","year":"1968","journal-title":"Blood"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-67-6-1268"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(196805)21:5<798::AID-CNCR2820210503>3.0.CO;2-Y"},{"key":"e_1_2_1_16_2","first-page":"326","article-title":"Abnormal granulocyte response to etiocholanolone in rheumatic diseases.","volume":"16","author":"Wolff SM","year":"1968","journal-title":"Clin Res"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780150105"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.3109\/rhe1.1957.3.issue-1-4.25"},{"key":"e_1_2_1_19_2","first-page":"1266","article-title":"Leukocytes and leukocyte antibodies in lupus erythematosus.","volume":"46","author":"S\u00f6nnichsen VM","year":"1967","journal-title":"Dermatol Wschr"}],"container-title":["Arthritis &amp; Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fart.1780160308","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/art.1780160308","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T18:15:29Z","timestamp":1696184129000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/art.1780160308"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1973,5]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1973,5]]}},"alternative-id":["10.1002\/art.1780160308"],"URL":"https:\/\/doi.org\/10.1002\/art.1780160308","archive":["Portico"],"relation":{},"ISSN":["0004-3591","1529-0131"],"issn-type":[{"value":"0004-3591","type":"print"},{"value":"1529-0131","type":"electronic"}],"subject":[],"published":{"date-parts":[[1973,5]]}}}