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The effect was usually noted within a week and did not persist when the drug was withdrawn. The percentage increase in mean absolute granulocyte count varied between 138% and 617% of control value in different patients; the lower values were observed in those patients with basal serum lithium concentrations less than 0.5 mEq\/liter. It is concluded that a consistent rise in peripheral blood granulocytes was achieved by lithium carbonate in a dosage of 900 mg daily in patients with Felty's syndrome.<\/jats:p>","DOI":"10.1002\/art.1780180217","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T16:28:06Z","timestamp":1171470486000},"page":"179-184","source":"Crossref","is-referenced-by-count":45,"title":["Efficacy of lithium in rheumatoid arthritis with granulocytopenia (felty's syndrome)"],"prefix":"10.1002","volume":"18","author":[{"given":"Ramesh C.","family":"Gupta","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William A.","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charley J.","family":"Smyth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,22]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.4159\/harvard.9780674423947"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(66)90141-3"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780110302"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.30.4.359"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-75-3-381"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1159\/000468046"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/cpt1971126923"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.127.11.1559"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3956(66)90008-2"},{"key":"e_1_2_1_11_2","first-page":"293","article-title":"Komplikationer ved lithium behandling (Complications of lithium therapy).","volume":"117","author":"Bille M","year":"1955","journal-title":"Ugeskr Laeger"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1973.tb01704.x"},{"key":"e_1_2_1_13_2","first-page":"175","article-title":"1958 revision of diagnostic criteria for rheumatoid arthritis","volume":"9","author":"Ropes MW","year":"1958","journal-title":"Bull Rheum Dis"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-2670(01)80708-X"},{"key":"e_1_2_1_15_2","first-page":"322","volume-title":"Questions of normality, Introduction to Statistical Analysis","author":"Dixon WJ","year":"1969"},{"key":"e_1_2_1_16_2","first-page":"177A","article-title":"Granulopoietic activity in Felty's syndrome.","volume":"22","author":"Gupta RC","year":"1974","journal-title":"Clin Res"},{"key":"e_1_2_1_17_2","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1182\/blood.V41.6.753.753","article-title":"Granulopoiesis in neutropenic disorders.","volume":"41","author":"Greenberg PL","year":"1973","journal-title":"Blood"},{"key":"e_1_2_1_18_2","first-page":"628","volume-title":"Granulocytopenia, Hematology","author":"Finch SC","year":"1972"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.223.6.671"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197305102881906"},{"key":"e_1_2_1_21_2","first-page":"455","volume-title":"Gold therapy for rheumatoid arthritis, Arthritis and Allied Conditions","author":"Freyberg RH","year":"1972"},{"key":"e_1_2_1_22_2","first-page":"35a","article-title":"Lithium therapy for neutropenias.","volume":"53","author":"Jacob E","year":"1974","journal-title":"J Clin Invest"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780160308"},{"key":"e_1_2_1_24_2","first-page":"362","volume-title":"Humoral regulation of haemopoiesis, Haemopoietic Cells","author":"Metcalf D","year":"1971"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3956(68)90047-2"}],"container-title":["Arthritis &amp; 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