{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:09:12Z","timestamp":1760954952944},"reference-count":11,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,12,15]],"date-time":"2005-12-15T00:00:00Z","timestamp":1134604800000},"content-version":"vor","delay-in-days":10881,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis &amp; Rheumatism"],"published-print":{"date-parts":[[1976,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A case of upper gastrointestinal tract hemorrhage secondary to esophageal varices in a patient with Felty's syndrome prompted a review of the pathogenesis and treatment of this condition. Six previously reported cases of this association were found. The clinical picture is that of long\u2010standing rheumatoid arthritis with severe articular and extraarticular manifestations including splenomegaly, depression of the blood elements, mild liver function abnormalities, portal hypertension without cirrhosis or portal vein obstruction, an elevated splenic blood flow, and a reduction in portal hypertension by simple splenectomy. The presence of portal hypertension with varices may be another indication for splenectomy in patients with Felty's syndrome.<\/jats:p>","DOI":"10.1002\/art.1780190204","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T17:46:04Z","timestamp":1171475164000},"page":"150-154","source":"Crossref","is-referenced-by-count":13,"title":["Esophageal varices in felty's syndrome. A case report and review of the literature"],"prefix":"10.1002","volume":"19","author":[{"given":"Raymond W.","family":"Klofkorn","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James C.","family":"Steigerwald","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David M.","family":"Mills","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charley J.","family":"Smyth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,15]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5689.131"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1042\/cs0380073"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.3109\/03009747309097147"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.30.4.359"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.14.1.84"},{"key":"e_1_2_1_7_2","first-page":"25","article-title":"Nodular regenerative hyperplasia of the liver in Felty's syndrome","volume":"169","author":"Blendis LM","year":"1974","journal-title":"Q J Med"},{"key":"e_1_2_1_8_2","first-page":"360","volume-title":"Extra\u2010articular rheumatoid disease, Arthritis and Allied Conditions","author":"Decker JL","year":"1972"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(66)91319-5"},{"key":"e_1_2_1_10_2","first-page":"441","article-title":"Splenic blood flow in cirrhosis and portal hypertension","volume":"34","author":"Williams R","year":"1968","journal-title":"Clin Sci"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(71)90234-8"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197406272902611"}],"container-title":["Arthritis &amp; Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fart.1780190204","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/art.1780190204","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T07:09:34Z","timestamp":1700723374000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/art.1780190204"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1976,3]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1976,3]]}},"alternative-id":["10.1002\/art.1780190204"],"URL":"https:\/\/doi.org\/10.1002\/art.1780190204","archive":["Portico"],"relation":{},"ISSN":["0004-3591","1529-0131"],"issn-type":[{"value":"0004-3591","type":"print"},{"value":"1529-0131","type":"electronic"}],"subject":[],"published":{"date-parts":[[1976,3]]}}}