{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T14:14:52Z","timestamp":1792073692532,"version":"4.4.0"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,12,11]],"date-time":"2005-12-11T00:00:00Z","timestamp":1134259200000},"content-version":"vor","delay-in-days":10816,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis &amp; Rheumatism"],"published-print":{"date-parts":[[1976,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The periarticular uptake of <jats:sup>99m<\/jats:sup>technetium\u2010labeled diphosphonate (<jats:sup>99m<\/jats:sup>TcDP) was compared in 12 patients hospitalized for psoriasis and in 12 hospitalized for other dermatoses not associated with arthropathy. The 12 patients with psoriasis had recent onset disease of less than 5 years duration; neither group had historical or clinical evidence of arthritis. All psoriatics had markedly abnormal scans with symmetrically increased periarticular uptake about the imaged joints. None of the controls had similar findings. In 4 patients scanned with <jats:sup>99m<\/jats:sup>technetium\u2010pertechnetate within 24 hours of their <jats:sup>99m<\/jats:sup>TcDP scan, no evidence of inflammatory synovitis was found. Three of these patients were serially imaged with <jats:sup>99m<\/jats:sup>TcDP at intervals of 2 weeks to 3 months after their initial study, when obvious clinical improvement in their psoriasis was apparent. Improvement in the radionuclide joint images was demonstrated in some of the patients, but none reverted to normal during the study period. In light of recent evidence for the preferential binding of <jats:sup>99m<\/jats:sup>TcDP to immature collagen, it is suggested that psoriasis may represent a generalized, but uncharacterized, collagen disorder present in bone as well as skin, linking the cutaneous disease with the potential for arthropathy.<\/jats:p>","DOI":"10.1002\/art.1780190313","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T17:45:49Z","timestamp":1171475149000},"page":"607-612","source":"Crossref","is-referenced-by-count":66,"title":["Periarticular uptake of <sup>99m<\/sup>technetium diphosphonate in psoriatics. Correlation with cutaneous activity"],"prefix":"10.1002","volume":"19","author":[{"given":"Thomas C.","family":"Namey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonard","family":"Rosenthall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,12,11]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"724","volume-title":"Psoriatic arthritis, Arthritis and Allied Conditions","author":"Sigler JW","year":"1972"},{"key":"e_1_2_1_3_2","first-page":"317","article-title":"Psoriatic arthritis in severe psoriasis","volume":"112","author":"Little H","year":"1975","journal-title":"Can Med Assoc J"},{"key":"e_1_2_1_4_2","first-page":"417","article-title":"Radio\u2010technetium polyphosphate joint imaging","volume":"15","author":"Desaulniers M","year":"1974","journal-title":"J Nucl Med"},{"key":"e_1_2_1_5_2","first-page":"823","article-title":"New bone scanning agent: 99mTc\u2010labeled 1\u2010hydroxy\u2010ethylidine\u20101, 1\u2010disodium phosphonate","volume":"13","author":"Castronovo FP","year":"1972","journal-title":"J Nucl Med"},{"key":"e_1_2_1_6_2","first-page":"1054","article-title":"Extra\u2010osseous non\u2010calcified soft tissue uptake of 99mTc\u2010poly\u2010phosphate","volume":"15","author":"Chauduri T","year":"1974","journal-title":"J Nucl Med"},{"key":"e_1_2_1_7_2","first-page":"1207","article-title":"Intense uptake of 99mTc\u2010diphosphonate by an extraosseous neurofibroma","volume":"15","author":"Nolan NG","year":"1974","journal-title":"J Nucl Med"},{"key":"e_1_2_1_8_2","first-page":"632","article-title":"Visualization of soft\u2010tissue malignancies by using 99mTc\u2010polyphosphate, pyrophosphate and diphosphonate","volume":"14","author":"Matsui K","year":"1973","journal-title":"J Nucl Med"},{"key":"e_1_2_1_9_2","first-page":"53","article-title":"Positive 99mTc\u2010polyphosphate scan in case of metastatic osteogenic sarcoma and hypertrophic pulmonary osteoarthropathy","volume":"15","author":"Brower AC","year":"1974","journal-title":"J Nucl Med"},{"key":"e_1_2_1_10_2","first-page":"238","article-title":"Technetium\u201099m\u2010diphosphonate accumulation in amyloid","volume":"16","author":"Van Antwerk JD","year":"1975","journal-title":"J Nucl Med"},{"key":"e_1_2_1_11_2","first-page":"58","article-title":"Distribution of 99mTc\u2010Sn diphosphonate and free 99mTc\u2010pertechnetate in selected soft and hard tissue","volume":"16","author":"Silberstein EB","year":"1975","journal-title":"J Nucl Med"},{"key":"e_1_2_1_12_2","first-page":"40","article-title":"Technetium\u201099m\u2010pyrophosphate: studies in vivo and in vitro","volume":"16","author":"Kaye M","year":"1975","journal-title":"J Nucl Med"},{"key":"e_1_2_1_13_2","first-page":"33","article-title":"Technetium\u201099m\u2010pyrophosphate kinetics and imaging in metabolic bone disease","volume":"16","author":"Rosenthall L","year":"1975","journal-title":"J Nucl Med"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197210122871503"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197210122871504"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(74)91262-8"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.33.5.446"},{"key":"e_1_2_1_18_2","first-page":"384","article-title":"The occurrence of antibodies against native human collagens in synovial fluids of patients with rheumatoid arthritis","volume":"18","author":"Andriopoulos NA","year":"1975","journal-title":"Arthritis Rheum"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780160302"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780140107"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197411142912001"},{"key":"e_1_2_1_22_2","unstructured":"RosenthallL NameyT: Unpublished data"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep13069808"},{"key":"e_1_2_1_24_2","first-page":"56","article-title":"Hydroxylation of proline in the biosynthesis of collagen","volume":"308","author":"Juva K","year":"1968","journal-title":"Acta Physiol Scand"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.104.1.57"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/0026-0495(66)90008-4"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1159\/000252101"}],"container-title":["Arthritis &amp; Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fart.1780190313","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/art.1780190313","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T07:19:56Z","timestamp":1700723996000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/art.1780190313"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1976,5]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1976,5]]}},"alternative-id":["10.1002\/art.1780190313"],"URL":"https:\/\/doi.org\/10.1002\/art.1780190313","archive":["Portico"],"relation":{},"ISSN":["0004-3591","1529-0131"],"issn-type":[{"value":"0004-3591","type":"print"},{"value":"1529-0131","type":"electronic"}],"subject":[],"published":{"date-parts":[[1976,5]]}}}