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Cigarette smokers with RA had significantly lower MMEFs than either nonsmokers with RA or smokers with degenerative joint disease. There was an increased prevalence of the Pi phenotype MS among the RA patients. Interstitial fibrosis, tobacco smoking, and protease inhibitor deficiencies were all significant factors in producing airway obstruction in patients with RA.<\/jats:p>","DOI":"10.1002\/art.1780190316","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T17:45:49Z","timestamp":1171475149000},"page":"623-628","source":"Crossref","is-referenced-by-count":87,"title":["Obstructive pulmonary disease in rheumatoid arthritis"],"prefix":"10.1002","volume":"19","author":[{"given":"Ronald L.","family":"Collins","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert A.","family":"Turner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Myron Johnson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy O.","family":"Whitley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ross L.","family":"McLean","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,11]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"347","volume-title":"Extra\u2010articular rheumatoid disease, Arthritis and Allied Conditions","author":"Decker JL","year":"1972"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/thx.8.1.29"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780060307"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/003693305700200502"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0007-0971(65)80050-X"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.26.6.467"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.37.3.321"},{"key":"e_1_2_1_9_2","first-page":"239","article-title":"Pulmonary infections in rheumatoid arthritis","volume":"36","author":"Walker WC","year":"1967","journal-title":"Q J Med"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.4933.228"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1964.03070120033008"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.63.1.27"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(62)90022-0"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.46.5.562"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1962.03620230215030"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-62-4-685"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1949.02900430001001"},{"key":"e_1_2_1_18_2","first-page":"57","article-title":"Spirometric standards for healthy nonsmoking adults","volume":"103","author":"Morris JF","year":"1971","journal-title":"Am Rev Resp Dis"},{"key":"e_1_2_1_19_2","first-page":"95","volume-title":"Respiratory Function in Disease","author":"Bates DV","year":"1970"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365517209102748"},{"key":"e_1_2_1_21_2","first-page":"145","volume-title":"Acid starch gel electrophoresis for detection of alpha\u2010antitrypsin variants (Pi types): outline of techniques employed currently, Pulmonary Emphysema and Proteolysis","author":"Fagerhol MK","year":"1972"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365517209102749"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423-0410.1969.tb00414.x"},{"key":"e_1_2_1_24_2","unstructured":"JohnsonAM:Alpha\u2010antitrypsin phenotyping at pH 8.6: identification of subtypes of PiM. 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