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The presence of HLA\u2010B8 was not correlated with parotid salivary flow, kerato\u2010conjunctivitis sicca, or focus score. Because of its association with a number of autoimmune diseases, including Sj\u00f6gren's syndrome, it is suggested that HLA\u2010B8 is genetically linked to an immune response gene(s) that predisposes the individual to autoimmune phenomena. The expression of autoimmunity may be determined by infectious or environmental factors.<\/jats:p>","DOI":"10.1002\/art.1780190508","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T17:40:11Z","timestamp":1171474811000},"page":"883-886","source":"Crossref","is-referenced-by-count":55,"title":["Association of Sj\u00f6gren's syndrome with HLA\u2010B8"],"prefix":"10.1002","volume":"19","author":[{"given":"Kenneth H.","family":"Fye","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul I.","family":"Terasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haralampos","family":"Moutsopoulos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Troy E.","family":"Daniels","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph P.","family":"Michalski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norman","family":"Talal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,11]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197304052881403"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197403072901008"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI106958"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI107123"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(74)92548-3"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-39-6-1115"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(72)92149-6"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(74)91450-0"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.2337\/diab.22.6.429"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.33.2.165"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(74)90417-4"},{"key":"e_1_2_1_13_2","doi-asserted-by":"crossref","first-page":"95","DOI":"10.3109\/10731197409118956","article-title":"An advanced design of the Carleon\u2010Crittendon cup for collection of parotid saliva","volume":"2","author":"Sproles AC","year":"1974","journal-title":"Biomater Med Devices Artif Organs"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-196811000-00006"},{"key":"e_1_2_1_15_2","unstructured":"GershwinME TerasakiPI GrawR et al: Increased frequency of HL\u2010A 8 in Sj\u00f6gren's syndrome.Tissue Antigens(in press)"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00336903"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780030402"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(70)91690-9"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.4.5731.340"},{"key":"e_1_2_1_20_2","first-page":"199","article-title":"The spectrum of benign to malignant lymphoproliferation in Sj\u00f6gren's syndrome","volume":"9","author":"Anderson LG","year":"1971","journal-title":"Clin Exp Immunol"},{"key":"e_1_2_1_21_2","first-page":"593","volume-title":"HL\u2010A phenotypes in Hodgkin's disease, Histocompatibility Testing 1972","author":"Kissmeyer\u2010Nielsen F","year":"1972"},{"key":"e_1_2_1_22_2","first-page":"555","volume-title":"Hodgkin's disease in a Caucasian population, Histocompatibility Testing 1972","author":"Lawler SD","year":"1972"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423-0410.1972.tb03839.x"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780170409"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197107222850403"}],"container-title":["Arthritis &amp; 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