{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T20:59:19Z","timestamp":1761512359744},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,12,13]],"date-time":"2005-12-13T00:00:00Z","timestamp":1134432000000},"content-version":"vor","delay-in-days":10118,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis &amp; Rheumatism"],"published-print":{"date-parts":[[1978,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Monozygotic twins with Klinefelter's syndrome were evaluated for two distinct illnesses. One subject had clinical and serologic evidence of systemic lupus erythematosus and no symptoms of muscle weakness. His identical twin had typical symptoms and laboratory evidence of myasthenia gravis. Antibodies to acetylcholine receptors were present in both subjects. These patients are discussed in relation to genetic, hormonal, and immunologic mechanisms involved in the pathogenesis of these two disorders.<\/jats:p>","DOI":"10.1002\/art.1780210303","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T17:53:15Z","timestamp":1171475595000},"page":"306-309","source":"Crossref","is-referenced-by-count":29,"title":["Monozygotic Twins With Klinefelter's Syndrome Discordant For Systemic Lupus Erythematosus And Symptomatic Myasthenia Gravis"],"prefix":"10.1002","volume":"21","author":[{"given":"Joseph P.","family":"Michalski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven M.","family":"Snyder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rima L.","family":"Mcleod","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Normal","family":"Talal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,13]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"743","article-title":"Family studies in systemic lupus erythematosus","volume":"2","author":"Leonhard ETG","year":"1967","journal-title":"Clin Exp Immunol"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780110103"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1963.03060080063022"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(74)90021-X"},{"key":"e_1_2_1_6_2","first-page":"39","volume-title":"Systemic lupus erythematosus, Primer on the Rheumatic Diseases","author":"Rodnan GP","year":"1973"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI108729"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780120312"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(76)90191-4"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(66)90519-8"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780180301"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780200103"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780160604"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780200315"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0090-1229(77)90027-7"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1177\/003693306000501001"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1966.00470090026003"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.186.4158.55"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.221.6.595"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.3109\/rhe1.1971.17.issue-1-4.19"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/0049-0172(75)90024-4"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(72)90021-6"},{"key":"e_1_2_1_23_2","first-page":"497","article-title":"Studies in myasthenia gravis: review of a twenty year experience in over 1200 patients","volume":"38","author":"Osserman KE","year":"1971","journal-title":"Mt Sinai J Med NY"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(75)90779-5"}],"container-title":["Arthritis &amp; Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fart.1780210303","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/art.1780210303","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T14:54:18Z","timestamp":1700751258000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/art.1780210303"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,4]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1978,4]]}},"alternative-id":["10.1002\/art.1780210303"],"URL":"https:\/\/doi.org\/10.1002\/art.1780210303","archive":["Portico"],"relation":{},"ISSN":["0004-3591","1529-0131"],"issn-type":[{"value":"0004-3591","type":"print"},{"value":"1529-0131","type":"electronic"}],"subject":[],"published":{"date-parts":[[1978,4]]}}}