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When treatment with 25 \u03bcg\/gm doses (intermittent or daily) was begun at 12 weeks of age, nephritis was accelerated in spite of transient reduction of anti\u2010DNA antibodies. When treatment was begun at 4 weeks, or when doses of 250 \u03bcg\/gm were given, no clinical effects were observed. In the mice with accelerated disease, delayed hypersensitivity and antibody responses to sheep erythrocytes increased; antibody responses to pneumococcal poiysaccharide were unaffected. It is possible that some increased immune responses associated with levamisole are undesirable in murine lupus.<\/jats:p>","DOI":"10.1002\/art.1780220305","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T18:48:09Z","timestamp":1171478889000},"page":"236-242","source":"Crossref","is-referenced-by-count":9,"title":["Alteration of lymphocyte function in nzb\/nzw mice"],"prefix":"10.1002","volume":"22","author":[{"given":"Bevra H.","family":"Hahn","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda 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