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In one case the foreign substances were removed by bilateral mastectomy with no discernible effects on the patient's clinical course. Histopathologic findings of the removed breasts demonstrated foreign body granulomas with calcification. The injected substance was identified as a mixture of liquid and solid paraffin. Human adjuvant disease might be caused by prolonged hypersensitization activated by the injected foreign materials which act as an adjuvant.<\/jats:p>","DOI":"10.1002\/art.1780220514","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T18:46:49Z","timestamp":1171478809000},"page":"532-537","source":"Crossref","is-referenced-by-count":119,"title":["Scleroderma After Cosmetic Surgery"],"prefix":"10.1002","volume":"22","author":[{"given":"Yasuo","family":"Kumagai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiyuki","family":"Abe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichi","family":"Shiokawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,11]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"9","article-title":"Hypergammaglobulinemia by prolonged adjuvanticity in men. 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