{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T16:11:38Z","timestamp":1783008698776,"version":"3.54.5"},"reference-count":21,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2005,12,11]],"date-time":"2005-12-11T00:00:00Z","timestamp":1134259200000},"content-version":"vor","delay-in-days":9629,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis &amp; Rheumatism"],"published-print":{"date-parts":[[1979,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Thirty\u2010two biopsies of kidneys and of normal skin were performed simultaneously on patients with systemic lupus erythematosus (SLE) to determine whether the deposition of immune reactants in skin was correlated with the severity of renal injury or with several serologic measures of systemic disease activity. Immunofluorescent deposits at the dermal\u2010epidermal junction (lupus band test) did not correlate with any clinical or histologic measures of glomerulonephritis or with serologic abnormalities. Immune deposits in dermal venules were found in 56% of the skin biopsies and were correlated with hypocomplementemia and higher levels of immune complexes in serum, and possibly with glomerular subendothelial electron dense deposits. Azathioprine therapy was correlated with absence of both subepidermal and vascular immune deposits. Immunofluorescent findings on serial skin biopsies on 13 patients were highly inconsistent. It is concluded that the lupus band test is clinically useful only as a diagnostic aid but not helpful in assessing renal or serologic activity of lupus, and that dermal vascular deposits of immunoglobulin or complement are more frequent than previously recognized and correlate with measures of circulating immune complexes.<\/jats:p>","DOI":"10.1002\/art.1780220809","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T18:41:05Z","timestamp":1171478465000},"page":"864-870","source":"Crossref","is-referenced-by-count":30,"title":["Simultaneous immunologic studies of skin and kidney in systemic lupus erythematosus"],"prefix":"10.1002","volume":"22","author":[{"given":"Richard J.","family":"Morris","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen J.","family":"Guggenheim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rawle M.","family":"Mcintosh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert L.","family":"Rubin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter F.","family":"Kohler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,12,11]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(77)90345-X"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-197103000-00001"},{"key":"e_1_2_1_4_2","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1001\/jama.1974.03230250023021","article-title":"Duration and death in systemic lupus erythematosus: an analysis of 249 cases","volume":"227","author":"Dubois EL","year":"1974","journal-title":"JAMA"},{"key":"e_1_2_1_5_2","doi-asserted-by":"crossref","first-page":"169s","DOI":"10.1084\/jem.134.3.169","article-title":"Systemic lupus erythematosus: prototype of immune complex nephritis in man","volume":"134","author":"Koffler D","year":"1971","journal-title":"J Exp Med"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.126.4.607"},{"key":"e_1_2_1_7_2","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1038\/jid.1963.140","article-title":"The application of the fluorescent antibody technique to the investigation of lupus erythematosus and various dermatoses","volume":"41","author":"Burnham TK","year":"1963","journal-title":"J Invest Dermatol"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1977.01640060126019"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(64)92917-4"},{"key":"e_1_2_1_10_2","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1001\/archderm.1971.04000130026003","article-title":"The immunofluorescent \u201cband\u201d test for lupus erythematosus","volume":"103","author":"Burnham TK","year":"1971","journal-title":"Arch Dermatol"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI107691"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1975.tb02245.x"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.222.8.935"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780190604"},{"key":"e_1_2_1_15_2","first-page":"643","article-title":"Preliminary criteria for classification of systemic lupus erythematosus","volume":"21","author":"Cohen AS","year":"1971","journal-title":"Bull Rheum Dis"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12512411"},{"key":"e_1_2_1_17_2","first-page":"79","article-title":"The course of lupus nephritis: contribution of serial renal biopsies","volume":"6","author":"Morel\u2010Maroger L","year":"1976","journal-title":"Adv Nephrol"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.161.3843.806"},{"key":"e_1_2_1_19_2","doi-asserted-by":"crossref","first-page":"232","DOI":"10.4049\/jimmunol.116.1.232","article-title":"Detection of immune complexes in unheated sera by a modified 125I\u2010Clq binding test","volume":"116","author":"Zubler RH","year":"1976","journal-title":"J Immunol"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI108262"},{"key":"e_1_2_1_21_2","first-page":"366","article-title":"Class of immunoglobulin deposition and prognosis in lupus nephritis","volume":"53","author":"Donadio JV","year":"1978","journal-title":"Mayo Clin Proc"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.223.7.798c"}],"container-title":["Arthritis &amp; Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fart.1780220809","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/art.1780220809","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T07:27:36Z","timestamp":1700724456000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/art.1780220809"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1979,8]]},"references-count":21,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1979,8]]}},"alternative-id":["10.1002\/art.1780220809"],"URL":"https:\/\/doi.org\/10.1002\/art.1780220809","archive":["Portico"],"relation":{},"ISSN":["0004-3591","1529-0131"],"issn-type":[{"value":"0004-3591","type":"print"},{"value":"1529-0131","type":"electronic"}],"subject":[],"published":{"date-parts":[[1979,8]]}}}