{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T00:56:19Z","timestamp":1700700979132},"reference-count":20,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2005,12,11]],"date-time":"2005-12-11T00:00:00Z","timestamp":1134259200000},"content-version":"vor","delay-in-days":9537,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis &amp; Rheumatism"],"published-print":{"date-parts":[[1979,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We proposed the hypothesis that there is an antigen on the hepatitis B virus (HBV) that cross\u2010reacts with a male associated antigen to explain four observations: 1) sex differences in the responses to HBV infection, 2) sex differences in the prevalence of chronic liver diseases associated with hepatitis B, 3) the association of parental responses to HBV with the sex ratio (at birth) of their offspring, and 4) the relation of kidney graft survival with the combination of anti\u2010HBs in the recipients and the sex of the organ donor. Patients with aplastic anemia treated with bone marrow transplantation from HLA identical sibling donors were studied to further test this hypothesis and the results provide additional support. Cross reactivity of HBsAg with H\u2010Y antigen, however, has not been demonstrated.<\/jats:p>","DOI":"10.1002\/art.1780221115","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T18:10:18Z","timestamp":1171476618000},"page":"1267-1273","source":"Crossref","is-referenced-by-count":8,"title":["Sex differences in response to hepatitis b virus"],"prefix":"10.1002","volume":"22","author":[{"given":"W. Thomas","family":"London","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,11]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.74.6.2561"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197702032960502"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(74)80033-4"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197407112910202"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1159\/000180739"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197701272960404"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-197712000-00002"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002480-197700230-00114"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-197704000-00007"},{"key":"e_1_2_1_11_2","first-page":"1170","article-title":"Hepatitis and renal transplants (Letter)","volume":"296","author":"Ponticelli C","year":"1977","journal-title":"N Engl J Med"},{"key":"e_1_2_1_12_2","first-page":"245","article-title":"Dialysis and kidney transplantation in Europe","volume":"55","author":"Hayry P","year":"1977","journal-title":"Med Biol"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-197803000-00013"},{"key":"e_1_2_1_14_2","first-page":"44","volume-title":"Interest of HBeAg in the study of immunogenetic factors influencing HBV infections in hemodialysed and kidney transplanted patients, Transplantation and Clinical Immunology, Proceedings of the 10th International Course","author":"Berochia S","year":"1979"},{"key":"e_1_2_1_15_2","first-page":"89","article-title":"Graft survival and response to hepatitis B virus in kidney recipients","volume":"11","author":"Toussaint C","year":"1979","journal-title":"Transplant Proc"},{"key":"e_1_2_1_16_2","first-page":"233","article-title":"Role of anti\u2010HBsAg in renal transplantation","volume":"7","author":"Vincenti F","year":"1978","journal-title":"Dialysis Transplant"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197711102971913"},{"key":"e_1_2_1_18_2","volume-title":"Unique hepatitis B surface antigen (HBsAg) subtype associated with chronic hemodialysis. 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