{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T13:39:42Z","timestamp":1756993182218},"reference-count":20,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2005,12,11]],"date-time":"2005-12-11T00:00:00Z","timestamp":1134259200000},"content-version":"vor","delay-in-days":9537,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis &amp; Rheumatism"],"published-print":{"date-parts":[[1979,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Low pH eluates were prepared from trophoblasts derived from 8 term human placentas. A qualitative analysis for immunoglobulins revealed the presence of IgG, IgA, and IgM in these eluates. IgG\u2010rich fractions were obtained by DEAE\u2010cellulose chromatography of ammonium sulfate\u2010concentrated eluates. These fractions were able to neutralize, in vitro, the catalytic activity of reverse transcriptases (RT) from several retroviruses. RT from baboon endogenous virus (BEV) seemed to be more susceptible to the neutralizing activity of some eluates. This was in contrast to RT from feline leukemia virus (FeLV) which were neutralized by eluates of leukocytes from chronic myelogenous leukemia. In contrast to previous and present results with purified IgG from leukemic leukocytes, the purified IgG from placenta eluates was incapable of RT neutralization. However, such purified IgG fractions inhibited mixed lymphocyte reactions.<\/jats:p>","DOI":"10.1002\/art.1780221120","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T18:10:18Z","timestamp":1171476618000},"page":"1308-1313","source":"Crossref","is-referenced-by-count":5,"title":["Placenta\u2010bound immunoglobulins"],"prefix":"10.1002","volume":"22","author":[{"given":"Abdo","family":"Jurjus","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David A.","family":"Wheeler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert C.","family":"Gallo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isaac P.","family":"Witz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,11]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/224914a0"},{"key":"e_1_2_1_3_2","first-page":"83","volume-title":"Immunologic coexistence in the maternal\u2010fetal relationship, Modern Perinatal Medicine","author":"Beer AE","year":"1975"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197611252952210"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780221119"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/50.4.1081"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.185.4154.864"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/52.3.987"},{"key":"e_1_2_1_9_2","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1093\/jnci\/52.4.1379","article-title":"Ultra structural comparison of placental virus with several type\u2010C oncogenic viruses","volume":"52","author":"Dalton AJ","year":"1974","journal-title":"J Natl Cancer Inst"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/275062a0"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.75.12.6263"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.204010"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-230X(08)60633-8"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/276230a0"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-1759(79)90180-7"},{"key":"e_1_2_1_16_2","first-page":"43","article-title":"Studies on human placenta. 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Characterization of immunoglobulins on the trophoblastic basement membrane","volume":"21","author":"Faulk WP","year":"1974","journal-title":"J Reprod Fert (suppl)"},{"key":"e_1_2_1_17_2","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.4049\/jimmunol.117.5_Part_1.1644","article-title":"Suppression of in vitro lymphocyte stimulation in mice by uterine and placental extracts","volume":"117","author":"Kouttab NM","year":"1976","journal-title":"J Immunol"},{"key":"e_1_2_1_18_2","first-page":"589","article-title":"Blocking antibodies eluted from human placenta","volume":"5","author":"Bonneau M","year":"1973","journal-title":"Transplant Proc"},{"key":"e_1_2_1_19_2","first-page":"89","article-title":"Demonstration, nature and properties of maternal antibodies fixed on placenta and directed against paternal antigens","volume":"21","author":"Voisin GA","year":"1974","journal-title":"J Reprod Fert (suppl)"},{"key":"e_1_2_1_20_2","first-page":"456","article-title":"Detection of receptors for immunoglobulin on human placenta by EA rosette formation","volume":"23","author":"Jenkinson EJ","year":"1976","journal-title":"Clin Exp Immunol"},{"key":"e_1_2_1_21_2","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.4049\/jimmunol.117.3.1033","article-title":"Inhibition of normal mouse lymphocyte mitogen responses by xenogeneic or allogeneic antibodies to the MuLV glycoprotein gp 71","volume":"117","author":"Lee JC","year":"1976","journal-title":"J Immunol"}],"container-title":["Arthritis &amp; Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fart.1780221120","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/art.1780221120","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T23:59:51Z","timestamp":1700697591000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/art.1780221120"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1979,11]]},"references-count":20,"journal-issue":{"issue":"11","published-print":{"date-parts":[[1979,11]]}},"alternative-id":["10.1002\/art.1780221120"],"URL":"https:\/\/doi.org\/10.1002\/art.1780221120","archive":["Portico"],"relation":{},"ISSN":["0004-3591","1529-0131"],"issn-type":[{"value":"0004-3591","type":"print"},{"value":"1529-0131","type":"electronic"}],"subject":[],"published":{"date-parts":[[1979,11]]}}}