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Levamisole was shown to alter antibody responses to tetanus and typhoid antigens, lymphocyte blastogenesis to phytohemagglutinins, and the number of null cells in peripheral blood. Agranulocytosis and rash resulted in discontinuation of the drug in one patient in each group. Though clearly effective, routine use of levamisole as a disease suppressant in rheumatoid arthritis must await more complete clarificatio of its association with agranulocytosis.<\/jats:p>","DOI":"10.1002\/art.1780230207","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T19:07:15Z","timestamp":1171480035000},"page":"172-182","source":"Crossref","is-referenced-by-count":20,"title":["Double\u2010blind placebo controlled crossover evaluation of levamisole in rheumatoid arthritis"],"prefix":"10.1002","volume":"23","author":[{"given":"Bruce","family":"Miller","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula 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