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In 5 cases the process was familial, with 17 persons in the oldest living generation (mean age 69 \u00b1 7.4) showing radiographic evidence of calcified cartilage. The clinical syndrome was characterized by a female predominance, late onset of symptoms with mild arthritic manifestations, and oligoarticular chondrocalcinosis. These data suggest that the familial type of CPPD crystal deposition disease is more frequent than formerly thought.<\/jats:p>","DOI":"10.1002\/art.1780230410","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T19:05:41Z","timestamp":1171479941000},"page":"471-478","source":"Crossref","is-referenced-by-count":18,"title":["Familial chondrocalcinosis"],"prefix":"10.1002","volume":"23","author":[{"given":"V.","family":"Rodriguez\u2010Valverde","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Tinture","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Zu\u00f1iga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Pe\u00f1a","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Gonzalez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,11]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(197605\/06)19:3 <275::AID-ART1780190702>3.0.CO;2-0"},{"key":"e_1_2_1_3_2","first-page":"1140","volume-title":"Pseudogout; articular chondrocalcinosis; calcium pyrophosphate crystal deposition disease, Arthritis and Allied Conditions","author":"McCarty DJ","year":"1972"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780180720"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.22.3.142"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.34.3.260"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(74)90612-3"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1964.03060360027006"},{"key":"e_1_2_1_9_2","first-page":"589","article-title":"Les chondrocalcinosis articulaires diffuses hereditaires","volume":"44","author":"Gaucher A","year":"1977","journal-title":"Rev Rhum"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.22.3.171"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.29.5.469"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(75)90463-5"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780130404"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780150307"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(197605\/06)19:3 <353::AID-ART1780190708>3.0.CO;2-Q"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(197605\/06)19:3 <307::AID-ART1780190705>3.0.CO;2-9"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.203.7.508"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(197605\/06)19:3 <307::AID-ART1780190705>3.0.CO;2-9"},{"key":"e_1_2_1_19_2","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1302\/0301-620X.56B2.246","article-title":"Pyrophosphate arthropathy: a clinical study of fifty cases","volume":"56","author":"Bjelle A","year":"1974","journal-title":"J Bone Joint Surg (Br)"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.132.1.87"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.226.1.42"},{"key":"e_1_2_1_22_2","first-page":"457","article-title":"Artritis aguda por cristales de pirofosfato calcio dihidratado: estudio clinico de 22 casos","volume":"149","author":"Rodriguez\u2010Valverde V","year":"1978","journal-title":"Rev Clin Esp"},{"key":"e_1_2_1_23_2","first-page":"39","article-title":"Pseudogota: espectro clinico. 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