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Necropsy findings in the myocardium included multiple areas of extensive lymphocytic infiltration and patches of fibrosis. Myocarditis has not previously been described in the adult with MCTD but may be an important complication in patients with a high titer of antibody to nuclear ribonucleoprotein.<\/jats:p>","DOI":"10.1002\/art.1780230706","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T19:03:47Z","timestamp":1171479827000},"page":"808-815","source":"Crossref","is-referenced-by-count":19,"title":["Myocarditis in mixed connective tissue disease"],"prefix":"10.1002","volume":"23","author":[{"given":"Patrick L.","family":"Whitlow","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James N.","family":"Gilliam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Chubick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morris","family":"Ziff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,23]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(72)90064-2"},{"key":"e_1_2_1_3_2","first-page":"828","article-title":"Mixed connective tissue disease","volume":"25","author":"Sharp GC","year":"1975","journal-title":"Bull Rheum Dis"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197611182952101"},{"key":"e_1_2_1_5_2","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.4049\/jimmunol.107.5.1281","article-title":"Characterization of a soluble nuclear ribonucleoprotein antigen reactive with SLE sera","volume":"107","author":"Mattioli M","year":"1971","journal-title":"J Immunol"},{"key":"e_1_2_1_6_2","first-page":"767","article-title":"Ribonucleoprotein antibodies: frequency and clinical significance in systemic lupus erythematosus, scleroderma and mixed connective tissue disease","volume":"82","author":"Parker MD","year":"1973","journal-title":"J Lab Clin Med"},{"key":"e_1_2_1_7_2","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1001\/archderm.1977.01640050043002","article-title":"Mixed connective tissue disease syndrome, cutaneous manifestations of patients with epidermal nuclear staining and high liter serum antibody to ribonuclease\u2010sensitive extractable nuclear antigen","volume":"113","author":"Gilliam JN","year":"1977","journal-title":"Arch Dermatol"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1978.tb06121.x"},{"key":"e_1_2_1_9_2","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1001\/archinte.1976.03630040029007","article-title":"Antibodies to components of ex\u2010tractable nuclear antigen: clinical characteristics of patients","volume":"136","author":"Farber SJ","year":"1976","journal-title":"Arch Intern Med"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(77)80555-6"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(78)90806-9"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780210712"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(78)90747-7"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780220606"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-89-5-619"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5047.732"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/0090-1229(72)90013-X"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1975.tb29197.x"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/0019-2791(66)90292-8"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1148\/120.2.433"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.51.5.902"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-197701000-00002"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-83-4-464"},{"key":"e_1_2_1_24_2","first-page":"404","article-title":"The evolving clinical spectrum of mixed connective tissue disease (MCTD)","volume":"18","author":"Hench PK","year":"1975","journal-title":"Arthritis Rheum"},{"key":"e_1_2_1_25_2","first-page":"643","article-title":"Preliminary criteria for the classification of systemic lupus erythematosus","volume":"21","author":"Cohen AS","year":"1971","journal-title":"Bull Rheum Dis"}],"container-title":["Arthritis &amp; 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