{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T15:28:18Z","timestamp":1791300498865,"version":"4.1.0"},"reference-count":19,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2005,11,23]],"date-time":"2005-11-23T00:00:00Z","timestamp":1132704000000},"content-version":"vor","delay-in-days":9245,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis &amp; Rheumatism"],"published-print":{"date-parts":[[1980,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Precipitating antibodies occurring in 26 \u201cpure\u201d polymyositis (PM) patients and 22 \u201cpure\u201d dermatomyositis (DM) patients were studied by double immunodiffusion using calf thymus nuclear extract and whole calf thymus extract. Seventeen of 26 (65%) PM sera and 13 of 22 (59%) DM sera showed positive reactions, and 18, 10, and 2 sera exhibited 1, 2, and 3 precipitin lines, respectively. Common specificities were established by immunodiffusion for the 11 PM and 6 DM sera with strong precipitin lines. These were classed into three groups of shared specificity and six reactions specific for individual sera. These 9 calf thymus antigens were shown to be different from the known soluble tisue antigens Sm, nuclear RNP, Ro, and La. A 600\u2010f old purification of the most frequently appearing system designated Jo\u20101 was achieved and its clinical specificity for patients with PM syndromes was established.<\/jats:p>","DOI":"10.1002\/art.1780230802","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T18:51:51Z","timestamp":1171479111000},"page":"881-888","source":"Crossref","is-referenced-by-count":298,"title":["Heterogeneity of precipitating antibodies in polymyositis and dermatomyositis"],"prefix":"10.1002","volume":"23","author":[{"given":"Masahiko","family":"Nishikai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morris","family":"Reichlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,11,23]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1942.02830210023006"},{"key":"e_1_2_1_3_2","first-page":"505","article-title":"Concept of collagen diseases in medicine","volume":"26","author":"Klemperer P","year":"1950","journal-title":"Am J Pathol"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5154.720"},{"key":"e_1_2_1_5_2","first-page":"12","article-title":"Polymyositis and myopathies in collagen diseases","volume":"14","author":"Nishikai M","year":"1974","journal-title":"Ryumachi"},{"key":"e_1_2_1_6_2","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1001\/archderm.1974.01630080051014","article-title":"Monoclonal gammopathy, penicillamine\u2010induced polymyositis, and systemic sclerosis","volume":"110","author":"Nishikai M","year":"1974","journal-title":"Arch Dermatol"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(72)92641-4"},{"key":"e_1_2_1_8_2","series-title":"International Congress Series. 299","volume-title":"Polymyositis and anti\u2010myoglobin antibody 99\u2013100 (abstract)","author":"Nishikai M","year":"1973"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.237.17.1842"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0090-1229(76)90145-8"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI108616"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-197707000-00001"},{"key":"e_1_2_1_13_2","first-page":"643","article-title":"Preliminary criteria for the classification of systemic lupus erythematosus","volume":"21","author":"Cohen AS","year":"1971","journal-title":"Bull Rheum Dis"},{"key":"e_1_2_1_14_2","first-page":"121","article-title":"Proposed diagnostic criteria for rheumatoid arthritis","volume":"7","author":"Ropes MW","year":"1956","journal-title":"Bull Rheum Dis"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4827(56)90107-0"},{"key":"e_1_2_1_16_2","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.4049\/jimmunol.107.5.1281","article-title":"Characterization of a soluble nuclear ribonucleoprotein antigen reactive with SLE sera","volume":"107","author":"Mattioli M","year":"1971","journal-title":"J Immunol"},{"key":"e_1_2_1_17_2","first-page":"377","article-title":"Determination of DNA and anti\u2010DNA by counterimmunoelectrophoresis: a rapid and sensitive assay (abstract)","volume":"14","author":"Davis JS","year":"1971","journal-title":"Arthritis Rheum"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.102.1.117"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.96.3.464"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780220719"}],"container-title":["Arthritis &amp; Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fart.1780230802","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/art.1780230802","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T16:08:53Z","timestamp":1700755733000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/art.1780230802"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,8]]},"references-count":19,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1980,8]]}},"alternative-id":["10.1002\/art.1780230802"],"URL":"https:\/\/doi.org\/10.1002\/art.1780230802","archive":["Portico"],"relation":{},"ISSN":["0004-3591","1529-0131"],"issn-type":[{"value":"0004-3591","type":"print"},{"value":"1529-0131","type":"electronic"}],"subject":[],"published":{"date-parts":[[1980,8]]}}}