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The present investigation demonstrates that EBV\u2010infected lymphocytes from patients with seronegative rheumatoid arthritis produce in vitro significantly less IgM rheumatoid factor than do normal lymphocytes. The results suggest that the peripheral blood of seronegative patients is deficient in the rheumatoid factor precursor B cells responsive to stimulation by Epstein Barr virus.<\/jats:p>","DOI":"10.1002\/art.1780240603","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T19:15:23Z","timestamp":1171480523000},"page":"770-773","source":"Crossref","is-referenced-by-count":9,"title":["Selective lymphocyte deficiency in seronegative rheumatoid arthritis"],"prefix":"10.1002","volume":"24","author":[{"given":"J.\u2010L.","family":"Pasquali","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Fong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. D.","family":"Tsoukas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. 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