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Mild flexion contractures of the interphalangeal joints were seen in 26 (19%), mainly in those children with more extensive and severe skin changes. Such contractures have been linked to microvascular complications of diabetes. The clinical and pathogenic similarities to progressive systemic sclerosis make the digital sclerosis of childhood diabetes a promising model for further rheumatologic study.<\/jats:p>","DOI":"10.1002\/art.1780251112","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T19:46:36Z","timestamp":1171482396000},"page":"1357-1361","source":"Crossref","is-referenced-by-count":64,"title":["Digital sclerosis in children with insulin\u2010dependent diabetes mellitus"],"prefix":"10.1002","volume":"25","author":[{"given":"James R.","family":"Seibold","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,11,28]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(76)80011-X"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198107233050403"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780220205"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780230319"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780230510"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.1.6.360"},{"key":"e_1_2_1_8_2","first-page":"92A","article-title":"Diabetes mellitus, short stature and joint stiffness: a new syndrome","volume":"22","author":"Rosenbloom AL","year":"1974","journal-title":"Clin Res"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-198104001-01129"},{"key":"e_1_2_1_10_2","doi-asserted-by":"crossref","first-page":"902","DOI":"10.2337\/diab.24.10.902","article-title":"Apparent accelerated aging of human collagen in diabetes mellitus","volume":"24","author":"Hamlin CR","year":"1975","journal-title":"Diabetes"},{"key":"e_1_2_1_11_2","doi-asserted-by":"crossref","first-page":"778","DOI":"10.2337\/diacare.20.10.778","article-title":"Increased collagen cross\u2010linkages in experimental diabetes: reversal by \u03b2\u2010aminopropionitrile and D\u2010penicillamine","volume":"29","author":"Chang K","year":"1980","journal-title":"Diabetes"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198010163031615"},{"key":"e_1_2_1_13_2","doi-asserted-by":"crossref","first-page":"284","DOI":"10.2337\/diab.26.4.284","article-title":"Abnormalities in proliferation and protein synthesis in skin fibroblast cultures from patients with diabetes mellitus","volume":"26","author":"Rowe DW","year":"1977","journal-title":"Diabetes"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.622567"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(77)91566-2"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-291X(81)80093-9"},{"key":"e_1_2_1_17_2","first-page":"762","volume-title":"Progressive systemic sclerosis (scleroderma), Arthritis and Allied Conditions","author":"Rodnan GP","year":"1979"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/0049-0172(75)90017-7"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-91-5-788"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.1.3.168"}],"container-title":["Arthritis &amp; Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fart.1780251112","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fart.1780251112","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/art.1780251112","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T22:48:57Z","timestamp":1700693337000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/art.1780251112"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,11]]},"references-count":19,"journal-issue":{"issue":"11","published-print":{"date-parts":[[1982,11]]}},"alternative-id":["10.1002\/art.1780251112"],"URL":"https:\/\/doi.org\/10.1002\/art.1780251112","archive":["Portico"],"relation":{},"ISSN":["0004-3591","1529-0131"],"issn-type":[{"value":"0004-3591","type":"print"},{"value":"1529-0131","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982,11]]}}}