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In 5 patients serum antiprecursor cell activity was detected. Blood monocytes failed to generate colony stimulating factor in 5 patients. Bone marrow\u2010directed immune mechanisms are heterogeneous and could play a role in the pathogenesis of neutropenia in some patients with Felty's syndrome.<\/jats:p>","DOI":"10.1002\/art.1780260802","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T20:12:40Z","timestamp":1171483960000},"page":"947-953","source":"Crossref","is-referenced-by-count":27,"title":["Heterogeneity of bone marrow\u2010directed immune mechanisms in the pathogenesis of neutropenia of felty's syndrome"],"prefix":"10.1002","volume":"26","author":[{"given":"Nabih I.","family":"Abdou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,28]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"16","article-title":"Chronic arthritis in the adult associated with splenomegaly and leukopenia","volume":"35","author":"Felty AR","year":"1924","journal-title":"Bull Johns Hopkins 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