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Cells within the palisading layer were \u201cmacrophage\u2010like,\u201d as indicated by staining for anti\u2010HLA\u2010DR and OKM1, and showed a high proliferative activity as seen by OKT9 reactivity. The granulation zone contained many (\u03b1Leu\u20101+) T cells in close contact with HLA\u2010DR\u2010expressing non\u2010T cells.<\/jats:p>","DOI":"10.1002\/art.1780261105","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T19:53:48Z","timestamp":1171482828000},"page":"1333-1339","source":"Crossref","is-referenced-by-count":21,"title":["Phenotypic characterization of cells within subcutaneous rheumatoid nodules"],"prefix":"10.1002","volume":"26","author":[{"given":"Eva","family":"Hedfors","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars","family":"Klareskog","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Staffan","family":"Lindblad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Urban","family":"Forsum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00f6ran","family":"Lindahl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,28]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"589","article-title":"The rheumatoid nodule: clinical significance (abstract)","volume":"21","author":"Scarola JA","year":"1978","journal-title":"Arthritis Rheum"},{"key":"e_1_2_1_3_2","first-page":"175","article-title":"1958 revision of diagnostic criteria for rheumatoid arthritis","volume":"9","author":"Ropes MW","year":"1958","journal-title":"Bull Rheum Dis"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/path.1700450111"},{"key":"e_1_2_1_5_2","first-page":"70","article-title":"Subcutaneous nodules of rheumatoid arthritis and rheumatic fever: a pathologic study","volume":"30","author":"Bennett GA","year":"1940","journal-title":"Arch Pathol"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3083.1982.tb00676.x"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3083.1978.tb00444.x"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.31.5.454"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.78.3.1791"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.314668"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.154.1.193"},{"key":"e_1_2_1_12_2","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.4049\/jimmunol.124.3.1301","article-title":"A monoclonal antibody reactive with the human cytotoxic\/suppressor T cell subset previously defined by a heteroantiserum termed TH2","volume":"3","author":"Reinherz EL","year":"1980","journal-title":"J Immunol"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.78.4.2541"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.78.5.3039"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.124.4.1943"},{"key":"e_1_2_1_16_2","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.4049\/jimmunol.127.3.1024","article-title":"A differentiation antigen of human NK and K cells identified by a monoclonal antibody (HNK\u20101)","volume":"127","author":"Abo T","year":"1979","journal-title":"J Immunol"},{"key":"e_1_2_1_17_2","first-page":"435","volume-title":"Pathology of rheumatoid arthritis and allied disorders, Arthritis and Allied Conditions","author":"Sokoloff L","year":"1979"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780261104"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1038\/288081a0"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.153.1.30"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.149.1.1"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3083.1981.tb00198.x"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(81)91107-7"},{"key":"e_1_2_1_24_2","first-page":"325","article-title":"In situ identification of T lymphocyte subsets and HLA\u2010DR expressing cells in the human skin tuberculin reaction","volume":"49","author":"Scheynius A","year":"1982","journal-title":"J Clin Exp Immunol"}],"container-title":["Arthritis &amp; 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