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Venom treated patients demonstrated an improvement in global efficacy and a decrease in the number of tender\/painful joints and swollen joints. Swollen joint index improved in 60% of venom treated patients. Other parameters did not demonstrate significant change. Reduction of joint swelling was followed by symptomatic improvement that was sometimes delayed by weeks. Reactions were limited to erythema at the injection site (all patients), local pruritis (two\u2010thirds of the patients), and fever with malaise (one\u2010third of the patients). Further study of this venom in rheumatoid arthritis appears warranted in view of its apparent favorable efficacy\u2010to\u2010toxicity ratio.<\/jats:p>","DOI":"10.1002\/art.1780270305","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T20:51:59Z","timestamp":1171486319000},"page":"277-284","source":"Crossref","is-referenced-by-count":27,"title":["The effects of a partially purified fraction of an ant venom in rheumatoid arthritis"],"prefix":"10.1002","volume":"27","author":[{"given":"Roy D.","family":"Altman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duane 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