{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T14:29:06Z","timestamp":1770992946496,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2005,11,28]],"date-time":"2005-11-28T00:00:00Z","timestamp":1133136000000},"content-version":"vor","delay-in-days":7728,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis &amp; Rheumatism"],"published-print":{"date-parts":[[1984,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Serologic studies on 114 patients with polymyositis and dermatomyositis revealed that 89% had either a precipitating antibody to antigens in calf thymus extract or a positive immunofluorescent reaction on HEp\u20102 cells, a human tissue culture line. Previously, the greatest proportion of polymyositis sera demonstrating positive serologic results (i.e., the proportion of patients' sera forming precipitates with calf thymus extract) was reported to be 60%. Use of the HEp\u20102 cell as immunofluorescent substrate enabled the detection of antibody in 89 (78%) of the sera, providing the additional probe which demonstrated specific antibody. Nuclear, cytoplasmic, and nucleolar staining are the most common patterns of immunofluorescence. The immunofluorescent patterns and individual precipitin reactions are related to each other and to the clinical syndromes in which they appear.<\/jats:p>","DOI":"10.1002\/art.1780271011","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T20:10:01Z","timestamp":1171483801000},"page":"1150-1156","source":"Crossref","is-referenced-by-count":117,"title":["Multiplicity of antibodies in myositis sera"],"prefix":"10.1002","volume":"27","author":[{"given":"Morris","family":"Reichlin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"Frank C.","family":"Arnett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,28]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-197707000-00001"},{"key":"e_1_2_1_3_2","volume-title":"Systemic Lupus Erythematosus: A Clinical Analysis","author":"Fries JF","year":"1975"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0090-1229(76)90145-8"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI108616"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780230802"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197502132920706"},{"key":"e_1_2_1_8_2","first-page":"643","article-title":"Preliminary criteria for the classification of systemic lupus erythematosus","volume":"21","author":"Cohen AS","year":"1971","journal-title":"Bull Rheum Dis"},{"key":"e_1_2_1_9_2","first-page":"1","article-title":"Preliminary criteria for the classification of systemic sclerosis (scleroderma)","volume":"31","author":"Masi AT","year":"1981","journal-title":"Bull Rheum Dis"},{"key":"e_1_2_1_10_2","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.4049\/jimmunol.107.5.1281","article-title":"Characterization of a soluble nuclear ribonucleoprotein antigen reactive with SLE sera","volume":"107","author":"Mattioli M","year":"1971","journal-title":"J Immunol"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780270114"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00915286"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780260714"},{"key":"e_1_2_1_14_2","first-page":"925","article-title":"The Jo\u20101 antibody system in myositis: relationship to clinical features and HLA","volume":"8","author":"Arnett FC","year":"1981","journal-title":"J Rheumatol"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/283220a0"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.76.11.5495"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/11.3.853"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/304177a0"},{"key":"e_1_2_1_19_2","first-page":"S24","article-title":"Antibody to coxsackie\u2010B virus: increased incidence in sera from children with recently diagnosed juvenile dermatomyositis (abstract)","volume":"26","author":"Christensen ML","year":"1983","journal-title":"Arthritis Rheum (suppl)"}],"container-title":["Arthritis &amp; Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fart.1780271011","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/art.1780271011","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T15:39:27Z","timestamp":1700753967000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/art.1780271011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,10]]},"references-count":18,"journal-issue":{"issue":"10","published-print":{"date-parts":[[1984,10]]}},"alternative-id":["10.1002\/art.1780271011"],"URL":"https:\/\/doi.org\/10.1002\/art.1780271011","archive":["Portico"],"relation":{},"ISSN":["0004-3591","1529-0131"],"issn-type":[{"value":"0004-3591","type":"print"},{"value":"1529-0131","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,10]]}}}