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Nifedipine significantly decreased lower esophageal sphincter pressure in these patients; this reduced lower esophageal sphincter pressure may cause gastroesophageal reflux. Thus, nifedipine may have detrimental effects on progressive systemic sclerosis patients.<\/jats:p>","DOI":"10.1002\/art.1780280504","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T20:58:10Z","timestamp":1171486690000},"page":"490-495","source":"Crossref","is-referenced-by-count":30,"title":["Nifedipine and esophageal dysfunction in progressive systemic sclerosis. 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