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Baseline levels of antibodies to diphtheria toxoid and tetanus toxoid decreased significantly after TLI in patients with lupus and RA, but antibody levels to pneumococcal polysaccharide remained unchanged. After TLI, the levels of antinuclear and anti\u2010DNA antibodies were reduced significantly in lupus, but levels of rheumatoid factor, antinuclear, and antigranulocyte antibodies all tended to increase in RA.<\/jats:p>","DOI":"10.1002\/art.1780290104","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T21:20:07Z","timestamp":1171488007000},"page":"26-31","source":"Crossref","is-referenced-by-count":19,"title":["Effect of total lymphoid irradiation on levels of serum autoantibodies in systemic lupus erythematosus and in rheumatoid arthritis"],"prefix":"10.1002","volume":"29","author":[{"given":"Amir","family":"Tanay","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerald","family":"Schiffman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Strober","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,29]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"366","volume-title":"Hodgkin's Disease","author":"Kaplan HS","year":"1980"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198110223051702"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780260801"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198110223051703"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780270501"},{"key":"e_1_2_1_7_2","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.4049\/jimmunol.132.2.1036","article-title":"Use of total lymphoid irradiation (TLI) in studies of the T cell\u2010dependence of autoantibody production in rheumatoid arthritis","volume":"132","author":"Tanay A","year":"1984","journal-title":"J Immunol"},{"key":"e_1_2_1_8_2","doi-asserted-by":"crossref","first-page":"979","DOI":"10.4049\/jimmunol.132.2.979","article-title":"Opposite effects of total lymphoid irradiation on T cell dependent and T cell independent antibody responses","volume":"132","author":"Tanay A","year":"1984","journal-title":"J Immunol"},{"key":"e_1_2_1_9_2","unstructured":"StroberS FieldE HoppeRT KotzinBL ShemeshO EnglemanEG RossJC MyersBD: Treatment of intractable lupus nephritis with total lymphoid irradiation.Ann Intern Med(in press)"},{"key":"e_1_2_1_10_2","first-page":"643","article-title":"Preliminary criteria for the classification of systemic lupus erythematosus","volume":"21","author":"Cohen AS","year":"1971","journal-title":"Bull Rheum Dis"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-90-6-887"},{"key":"e_1_2_1_12_2","volume-title":"Immunofluorescence Detection of Autoimmune Diseases","author":"Cavallaro JJ","year":"1979"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.137.5.1275"},{"key":"e_1_2_1_14_2","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.4049\/jimmunol.105.6.1581","article-title":"Evidence for the existence of two functionally distinct types of cells that regulate the antibody response to type III pneumococcal polysaccharide","volume":"105","author":"Baker PJ","year":"1970","journal-title":"J Immunol"},{"key":"e_1_2_1_15_2","doi-asserted-by":"crossref","first-page":"220","DOI":"10.4049\/jimmunol.127.1.220","article-title":"Human lymphocytes can generate thymus\u2010independent as well as thymus\u2010dependent anti\u2010hapten plaque\u2010forming cell responses in vitro","volume":"127","author":"Golding B","year":"1981","journal-title":"J Immunol"},{"key":"e_1_2_1_16_2","doi-asserted-by":"crossref","first-page":"2309","DOI":"10.4049\/jimmunol.122.6.2309","article-title":"Characteristics of in vitro production of antibodies to DNA in normal and autoimmune mice","volume":"122","author":"Sawada S","year":"1979","journal-title":"J Immunol"}],"container-title":["Arthritis &amp; 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