{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T22:54:19Z","timestamp":1762210459707},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,11,29]],"date-time":"2005-11-29T00:00:00Z","timestamp":1133222400000},"content-version":"vor","delay-in-days":7213,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis &amp; Rheumatism"],"published-print":{"date-parts":[[1986,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Several forms of seronegative polyarthritis are strongly associated with HLA\u2010B27, and a number of microorganisms have been implicated in the etiology of these diseases. To explain the association between HLA\u2010B27 and arthritis initiated by infection with these organisms, it has been proposed that there is immunologic cross\u2010reactivity between the B27 molecule and 1 or more microbial antigens, and that this cross\u2010reactivity leads to tolerance to such infection and\/or to the production of anti\u2010HLA\u2010B27 cross\u2010reactive antibodies. Such cross\u2010reactive antibodies were detected in the sera of only 2 of 63 patients recently infected with <jats:italic>Shigella flexneri, Campylobacter jejuni<\/jats:italic>, or <jats:italic>Yersinia enterocolitica<\/jats:italic> who had highly significant antibody levels against the infecting bacterial species. Most striking was the absence of anti\u2010HLA\u2010B27 antibody in the serum of 16 of 17 patients who developed reactive arthritis following <jats:italic>Yersinia<\/jats:italic> infection.<\/jats:p>","DOI":"10.1002\/art.1780290307","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T21:14:04Z","timestamp":1171487644000},"page":"352-357","source":"Crossref","is-referenced-by-count":16,"title":["Anti\u2010HLA\u2013B27 antibodies in sera from patients with gram\u2010negative bacterial infections"],"prefix":"10.1002","volume":"29","author":[{"given":"Druie","family":"Cavender","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morris","family":"Ziff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,29]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0049-0172(77)90023-3"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198312293092604"},{"key":"e_1_2_1_4_2","first-page":"1","article-title":"Reiter's disease: a study of 344 cases observed in Finland","volume":"212","author":"Paronen I","year":"1948","journal-title":"Acta Med Scand (suppl)"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.3109\/rhe1.1969.15.issue-1-4.32"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0954-6820.1964.tb00634.x"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-86-4-444"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.198.7.693"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.39.5.431"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.3109\/03009748109095295"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.6344216"},{"key":"e_1_2_1_12_2","first-page":"85","article-title":"Ankylosing spondylitis HLA\u2010B27 and Klebsiella. I. Crossreactivity studies with rabbit antisera","volume":"61","author":"Welsh J","year":"1980","journal-title":"Br J Exp Pathol"},{"key":"e_1_2_1_13_2","first-page":"92","article-title":"Ankylosing spondylitis, HLA\u2010B27 and Klebsiella. II. Crossreactivity studies with human tissue typing sera","volume":"61","author":"Avakian H","year":"1980","journal-title":"Br J Exp Pathol"},{"key":"e_1_2_1_14_2","first-page":"607","article-title":"Identification of HLA\u2010B27MI and \u2010M2 crossreactive antigens in Klebsiella, Shigella and Yersinia","volume":"52","author":"Van Bohemen CG","year":"1984","journal-title":"Immunology"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.40.4.400"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-14-4-451"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.41.4.433"},{"key":"e_1_2_1_18_2","first-page":"102","article-title":"Klebsiella related antigens in ankylosing spondylitis","volume":"10","author":"Beaulieu AD","year":"1983","journal-title":"J Rheumatol"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.1983.tb00708.x"},{"key":"e_1_2_1_20_2","first-page":"865","article-title":"The link between genes and disease","volume":"79","author":"Ebringer A","year":"1978","journal-title":"New Scientist"},{"key":"e_1_2_1_21_2","first-page":"165","volume-title":"Antibodies to enterobacterial cell envelope antigens in ankylosing spondylitis","author":"Van Bohemen CG","year":"1985"},{"key":"e_1_2_1_22_2","first-page":"S32","article-title":"HLA\u2010B27 loss variants of a B27+ lymphoblastoid cell line (abstract)","volume":"27","author":"Nicklas JA","year":"1984","journal-title":"Arthritis Rheum (suppl)"},{"key":"e_1_2_1_23_2","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1128\/iai.44.2.292-298.1984","article-title":"Human serum antibody to Campylobacter jejuni infection as measured in an enzyme\u2010labeled immunoabsorbent assay","volume":"44","author":"Blaser MJ","year":"1984","journal-title":"Infect Immun"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.44.3.169"},{"key":"e_1_2_1_25_2","first-page":"303","article-title":"Absence of lymphocytotoxic antibodies in patients with Yersinia\u2010induced arthritis, Reiter's syndrome and ankylosing spondylitis","volume":"2","author":"Kono DH","year":"1984","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/0198-8859(82)90031-3"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0039.1983.tb01203.x"}],"container-title":["Arthritis &amp; Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fart.1780290307","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/art.1780290307","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T22:43:56Z","timestamp":1700693036000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/art.1780290307"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,3]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1986,3]]}},"alternative-id":["10.1002\/art.1780290307"],"URL":"https:\/\/doi.org\/10.1002\/art.1780290307","archive":["Portico"],"relation":{},"ISSN":["0004-3591","1529-0131"],"issn-type":[{"value":"0004-3591","type":"print"},{"value":"1529-0131","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,3]]}}}