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This complication occurred in 6 of 96 pregnancies in women with anti\u2010SS\u2010A and was associated with high\u2010titer maternal antibody. The overall risk of a woman with lupus having an infant with congenital heart block was estimated to be 1:60, but the risk was considerably higher (1:20) if anti\u2010SS\u2010A antibody was present.<\/jats:p>","DOI":"10.1002\/art.1780291013","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T21:17:48Z","timestamp":1171487868000},"page":"1269-1273","source":"Crossref","is-referenced-by-count":135,"title":["Anti\u2010SS\u2010A antibodies and fetal outcome in maternal systemic lupus erythematosus"],"prefix":"10.1002","volume":"29","author":[{"given":"Rosalind","family":"Ramsey\u2010Goldman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Hom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jau\u2010Shyong","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gayle Casterline","family":"Ziegler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leslie E.","family":"Kahl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginia D.","family":"Steen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald E.","family":"Laporte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"THOMAS A.","family":"Medsger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,11,29]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"936","volume-title":"Systemic lupus erythematosus: immunologic aspects, Arthritis and Allied Conditions","author":"Tan EM","year":"1985"},{"key":"e_1_2_1_3_2","first-page":"178","article-title":"Systemic lupus erythematosus management during pregnancy","volume":"51","author":"Zurier RB","year":"1977","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(70)90620-4"},{"key":"e_1_2_1_5_2","first-page":"281","volume-title":"The vital statistics of reproduction, Obstetrics and Gynecology","author":"Thompson JF","year":"1982"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-198411000-00003"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198307283090403"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780251101"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1109\/MC.1979.1658533"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(84)70198-8"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI110523"},{"key":"e_1_2_1_12_2","first-page":"145","volume-title":"Case\u2010Control Studies: Design, Conduct, Analysis","author":"Schlesselman J","year":"1982"},{"key":"e_1_2_1_13_2","first-page":"1269","article-title":"A method of estimating comparative ranges from clinical data: applications to cancer of the lung, breast and cervix","volume":"11","author":"Cornfield J","year":"1951","journal-title":"JNCI"},{"key":"e_1_2_1_14_2","first-page":"189","article-title":"The clinical significance of autoantibodies to a soluble cytoplasmic antigen in systemic lupus erythematosus and other connective tissue diseases","volume":"6","author":"Maddison P","year":"1979","journal-title":"J Rheumatol"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780230304"},{"key":"e_1_2_1_16_2","first-page":"99","article-title":"Outcome of pregnancy in systemic lupus erythematosus","volume":"70","author":"Grigor RR","year":"1977","journal-title":"Proc R Soc Med"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12277079"}],"container-title":["Arthritis &amp; 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