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Eight of the 32 patients required adjunctive immunosuppressive drug therapy to maintain improvement. Four patients died after total lymphoid irradiation; the causes of death were acute myocardial infarction (1 patient), pulmonary embolism (1 patient), and rheumatoid lung disease complicated by respiratory infection (2 patients). After therapy, patients exhibited a prolonged reduction in the number and function of circulating T helper cells.<\/jats:p>","DOI":"10.1002\/art.1780300101","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T21:48:31Z","timestamp":1171489711000},"page":"1-10","source":"Crossref","is-referenced-by-count":39,"title":["Long\u2010term followup of rheumatoid arthritis patients treated with total lymphoid irradiation"],"prefix":"10.1002","volume":"30","author":[{"given":"A.","family":"Tanay","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. 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