{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:19:11Z","timestamp":1790741951950,"version":"4.1.0"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,11,29]],"date-time":"2005-11-29T00:00:00Z","timestamp":1133222400000},"content-version":"vor","delay-in-days":6848,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis &amp; Rheumatism"],"published-print":{"date-parts":[[1987,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Recent observations that juvenile dermatomyositis (JDMS) may be a heterogenous disorder, in both its clinical course and prognosis, suggest that subgroups of patients with this disease may respond to various modes of therapy. Therefore, current treatment recommendations of daily, long\u2010term oral corticosteroid treatment, with its attendant side effects, may not be necessary for all children with JDMS. We report the results of treatment with high\u2010dose, pulse intravenous methylprednisolone in 7 children with JDMS, 3 of whom had an excellent response with complete remission and no need for daily steroid therapy. We suggest that patients with early, mild JDMS may be candidates for therapy with intravenous methylprednisolone.<\/jats:p>","DOI":"10.1002\/art.1780300312","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T21:40:02Z","timestamp":1171489202000},"page":"328-334","source":"Crossref","is-referenced-by-count":71,"title":["Intravenous pulse methylprednisolone treatment of juvenile dermatomyositis"],"prefix":"10.1002","volume":"30","author":[{"given":"Ronald M.","family":"Laxer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonard D.","family":"Stein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ross E.","family":"Petty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,11,29]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"407","volume-title":"Dermatomyositis, Textbook of Pediatric Rheumatology","author":"Sullivan DB","year":"1982"},{"key":"e_1_2_1_3_2","first-page":"327","article-title":"Dermatomyositis in the pediatric patient","volume":"20","author":"Sullivan DB","year":"1977","journal-title":"Arthritis Rheum"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(76)91272-1"},{"key":"e_1_2_1_5_2","first-page":"486","article-title":"Megadose corticosteroids therapy in systemic lupus erythematosus","volume":"7","author":"Fessel WJ","year":"1980","journal-title":"J Rheumatol"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1159\/000249745"},{"key":"e_1_2_1_7_2","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1542\/peds.65.5.989","article-title":"Prolonged use of large intravenous steroid pulses in the rheumatoid diseases of childhood","volume":"65","author":"Miller JJ","year":"1980","journal-title":"Pediatrics"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197502132920706"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(84)80012-8"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(83)80706-9"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780250203"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1985.tb00465.x"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-94-1-21"},{"key":"e_1_2_1_14_2","first-page":"287","article-title":"Lymphocyte subpopulation alterations induced by intravenous megadose pulse methylprednisolone","volume":"11","author":"Silverman ED","year":"1984","journal-title":"J Rheumatol"},{"key":"e_1_2_1_15_2","first-page":"529","article-title":"Variable effects of corticosteroid treatment on serum enzyme activities in Duchenne's muscular dystrophy","volume":"17","author":"Cohen L","year":"1977","journal-title":"Res Commun Chem Pathol Pharmacol"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-128-33107"},{"key":"e_1_2_1_17_2","first-page":"677","article-title":"Complications of intravenous methylprednisolone pulse therapy (abstract)","volume":"23","author":"Garrett R","year":"1980","journal-title":"Arthritis Rheum"}],"container-title":["Arthritis &amp; Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fart.1780300312","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/art.1780300312","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T08:41:36Z","timestamp":1700728896000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/art.1780300312"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,3]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1987,3]]}},"alternative-id":["10.1002\/art.1780300312"],"URL":"https:\/\/doi.org\/10.1002\/art.1780300312","archive":["Portico"],"relation":{},"ISSN":["0004-3591","1529-0131"],"issn-type":[{"value":"0004-3591","type":"print"},{"value":"1529-0131","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,3]]}}}