{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T06:55:41Z","timestamp":1761807341851},"reference-count":15,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2005,11,29]],"date-time":"2005-11-29T00:00:00Z","timestamp":1133222400000},"content-version":"vor","delay-in-days":6298,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis &amp; Rheumatism"],"published-print":{"date-parts":[[1988,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We conducted HLA\u2013B27 tissue typing assessments on 430 consecutive children whose main symptom at presentation to our clinic was arthritis\/arthralgia. Eighty\u2010five of them (20%) had the B27 antigen. Thirty\u2010six of these children were reexamined after a mean followup period of 8.9 years. Although most had definable rheumatic diseases, only 2 met the New York criteria for ankylosing spondylitis (AS). Children with HLA\u2013B27 and arthritis\/arthralgia, although at increased risk of developing AS, have diverse diagnostic and clinical outcomes. The AS criteria used to diagnose the disease in adults may not be appropriate for use in children.<\/jats:p>","DOI":"10.1002\/art.1780310912","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T22:19:00Z","timestamp":1171491540000},"page":"1165-1170","source":"Crossref","is-referenced-by-count":31,"title":["HLA\u2013B27\u2013associated arthropathy in childhood: long\u2010term clinical and diagnostic outcome"],"prefix":"10.1002","volume":"31","author":[{"given":"Kathleen A.","family":"Sheerin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward H.","family":"Giannini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Earl J.","family":"Brewer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karyl S.","family":"Barron","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,29]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/XXII.suppl_2.104"},{"issue":"4","key":"e_1_2_1_3_2","first-page":"S79","article-title":"The natural history of juvenile ankylosing spondylitis: a case\u2010control study of juvenile and adult\u2010onset disease (abstract)","volume":"24","author":"Marks S","year":"1981","journal-title":"Arthritis Rheum"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(69)80032-6"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780140505"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780250902"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.3109\/03009748309098542"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(82)80746-4"},{"issue":"4","key":"e_1_2_1_9_2","first-page":"S151","article-title":"Children at risks for developing ankylosing spondylitis (abstract)","volume":"25","author":"Barron KS","year":"1982","journal-title":"Arthritis Rheum"},{"key":"e_1_2_1_10_2","first-page":"453","article-title":"New York symposium on population studies in the rheumatic diseases: New diagnostic criteria","volume":"17","author":"Bennett PH","year":"1967","journal-title":"Bull Rheum Dis"},{"key":"e_1_2_1_11_2","first-page":"195","article-title":"Current proposed revision of JRA criteria","volume":"20","author":"Brewer EJ","year":"1977","journal-title":"Arthritis Rheum"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(80)90006-6"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(76)81043-8"},{"key":"e_1_2_1_14_2","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1542\/peds.56.4.498","article-title":"Histocompatibility locus antigen W7 and the rheumatic diseases","volume":"56","author":"Rachelefsky GS","year":"1975","journal-title":"Pediatrics"},{"key":"e_1_2_1_15_2","volume-title":"Arthritis as a manifestation of connective tissue diseases, Arthritis in Childhood","author":"Jacobs JC","year":"1981"},{"issue":"2","key":"e_1_2_1_16_2","article-title":"Ankylosing spondylitis without HLA B27","volume":"22","author":"Jajic IVO","year":"1983","journal-title":"Br J Rheumatol"}],"container-title":["Arthritis &amp; Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fart.1780310912","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/art.1780310912","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T16:56:37Z","timestamp":1700758597000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/art.1780310912"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,9]]},"references-count":15,"journal-issue":{"issue":"9","published-print":{"date-parts":[[1988,9]]}},"alternative-id":["10.1002\/art.1780310912"],"URL":"https:\/\/doi.org\/10.1002\/art.1780310912","archive":["Portico"],"relation":{},"ISSN":["0004-3591","1529-0131"],"issn-type":[{"value":"0004-3591","type":"print"},{"value":"1529-0131","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,9]]}}}