{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T06:47:27Z","timestamp":1757573247365},"reference-count":13,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,12,9]],"date-time":"2005-12-09T00:00:00Z","timestamp":1134086400000},"content-version":"vor","delay-in-days":5790,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis &amp; Rheumatism"],"published-print":{"date-parts":[[1990,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Two cases of DNA autosensitivity in Japanese sisters are reported. Both patients developed painful ecchymoses and other bleeding disorders. Skin tests with autologous leukocyte lysates and calf thymus DNA produced intermediate\u2010type reactions that were identical to spontaneous skin reactions. Pretreatment of DNA with either DNase or chloroquine sulfate inhibited these reactions. Our studies suggest that anti\u2010DNA antibodies might contribute to the clinical symptoms of this disorder.<\/jats:p>","DOI":"10.1002\/art.1780330221","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T23:03:53Z","timestamp":1171494233000},"page":"287-292","source":"Crossref","is-referenced-by-count":2,"title":["Dna autosensitivity in two japanese sisters"],"prefix":"10.1002","volume":"33","author":[{"given":"Susumu","family":"Sugai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukio","family":"Yasuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiro","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Sawada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junko","family":"Tachibana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susumu","family":"Konda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirohisa","family":"Kitada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroko","family":"Nakaizumi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sadao","family":"Tsukada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,9]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196103162641103"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196211292672201"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-60-5-886"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-196602000-00003"},{"key":"e_1_2_1_6_2","first-page":"108","article-title":"Autoerythrocyte sensitization reproducible by both autologous red cells and heterologous DNA.","volume":"37","author":"Spiera H","year":"1970","journal-title":"Mt Sinai J Med (NY)"},{"key":"e_1_2_1_7_2","first-page":"67","article-title":"Possible role of bradykinin in a patient with recurrent cutaneous ecchymoses (DNA sensitization).","volume":"8","author":"Leiba H","year":"1972","journal-title":"Isr J Med Sci"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12676193"},{"key":"e_1_2_1_9_2","doi-asserted-by":"crossref","first-page":"345","DOI":"10.2340\/0001555560345348","article-title":"Autosensitization to DNA.","volume":"60","author":"Brauner F","year":"1980","journal-title":"Acta Derm Venereol (Stockh)"},{"key":"e_1_2_1_10_2","first-page":"9","article-title":"A case of DNA autosensitivity.","volume":"31","author":"Sugai S","year":"1982","journal-title":"Jpn J Allergol"},{"key":"e_1_2_1_11_2","volume-title":"Passive cutaneous anaphylaxis (PCA), Handbook of Experimental Immunology","author":"Brodklehurst WE","year":"1973"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00915006"},{"key":"e_1_2_1_13_2","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/S0021-9258(18)38529-6","article-title":"Interaction of chloroquine with nucleic acids and nucleoproteins.","volume":"199","author":"Parker FS","year":"1952","journal-title":"J Biol Chem"},{"key":"e_1_2_1_14_2","doi-asserted-by":"crossref","first-page":"1852","DOI":"10.4049\/jimmunol.133.4.1852","article-title":"Detection of masked anti\u2010DNA antibodies in lupus sera by a monoclonal anti\u2010idiotype.","volume":"133","author":"Halpern R","year":"1984","journal-title":"J Immunol"}],"container-title":["Arthritis &amp; Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fart.1780330221","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/art.1780330221","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T22:21:24Z","timestamp":1700778084000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/art.1780330221"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,2]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1990,2]]}},"alternative-id":["10.1002\/art.1780330221"],"URL":"https:\/\/doi.org\/10.1002\/art.1780330221","archive":["Portico"],"relation":{},"ISSN":["0004-3591","1529-0131"],"issn-type":[{"value":"0004-3591","type":"print"},{"value":"1529-0131","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,2]]}}}