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To determine potential antibody differences between IgG aPL\u2010positive women with and without fetal death, we studied aPL isotype, subclass, anticoagulant activity, phospholipid specificity, and antibody avidity in selected sera from pregnant SLE patients with high\u2010titer IgG aPL. For controls, we selected sera from pregnant SLE patients who had negative results on tests for IgG aPL (with and without fetal loss). None of the specified antibody characteristics distinguished between the aPL\u2010positive patient groups, nor were other specificities defined in IgG aPL\u2010negative sera from women with fetal death. Although high\u2010titer aPL is a good predictor of fetal death, currently known characteristics, other than a high titer of aPL, do not identify which women will experience this complication.<\/jats:p>","DOI":"10.1002\/art.1780330406","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T23:29:27Z","timestamp":1171495767000},"page":"501-504","source":"Crossref","is-referenced-by-count":40,"title":["Characteristics of high\u2010titer igg antiphospholipid antibody in systemic lupus erythematosus patients with and without fetal death"],"prefix":"10.1002","volume":"33","author":[{"given":"Tasneem","family":"Qamar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roger 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