{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T05:38:18Z","timestamp":1757569098812},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2005,12,9]],"date-time":"2005-12-09T00:00:00Z","timestamp":1134086400000},"content-version":"vor","delay-in-days":5305,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis &amp; Rheumatism"],"published-print":{"date-parts":[[1991,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In 1986, we diagnosed and treated 4 patients, all members of 1 rural family, who presented simultaneously with a polymyositis\u2010like syndrome, anticytoplasmic antibodies (on HEp\u20102 cells), and precipitating antibodies of anti\u2010Jo\u20101 and anti\u2010PM\u2010Scl specificities. Serum samples from these patients reacted by immunodiffusion against serum from a rodent that had been caught in the patients' house. The precipitin line showed complete immunologic identity with anti\u2010Jo\u20101. To study the specificity of this serum\u2010serum reaction, 2 mice (<jats:italic>Mus musculus<\/jats:italic>) and 1 rat (<jats:italic>Rattus rattus<\/jats:italic>) from the neighboring areas of the patients' house were caught and killed. Sections of the liver, kidney, spleen, and skeletal muscle were processed for histopathologic examination and for direct and indirect immunofluorescence studies of the patients' sera. The rodents' sera were tested by immunodiffusion against serum samples from 25 patients with systemic lupus erythematosus, 11 with rheumatoid arthritis, 6 with mixed connective tissue disease, and 11 with various other rheumatic diseases, as well as 16 healthy controls. A serum\u2010serum precipitin reaction was noted between the rodents' sera and sera from 2 of the patients with polymyositis\u2010like syndrome. A distinct, but weaker, reaction was found with 2 lupus patients' sera (8%), and with 1 healthy control serum (6%). The rodents' sera were antinuclear antibody positive by indirect immunofluorescence on HEp\u20102 cells. These results, suggest that some rodents could be carriers of an as\u2010yet\u2010unknown transmissible agent that, in susceptible individuals, induces clinical and serologic manifestations similar to those of polymyositis.<\/jats:p>","DOI":"10.1002\/art.1780340616","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T23:40:35Z","timestamp":1171496435000},"page":"744-750","source":"Crossref","is-referenced-by-count":6,"title":["Acute familial myositis with a common autoimmune response"],"prefix":"10.1002","volume":"34","author":[{"given":"Ignacio Garc\u00eda","family":"de la Torre","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Ram\u00edrez\u2010Casillas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lourdes","family":"Hern\u00e1ndez\u2010Vazquez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,9]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197502132920706"},{"key":"e_1_2_1_3_2","volume-title":"Inflammatory diseases of muscle, Textbook of Rheumatology","author":"Bradley WG","year":"1985"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880050802"},{"key":"e_1_2_1_5_2","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0307-742X(21)00481-1","article-title":"Aetiology: inflammatory disorders of muscle","volume":"10","author":"Denman AM","year":"1984","journal-title":"Clin Rheum Dis"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01641089"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/140.2.239"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780270411"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780300509"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780251101"},{"key":"e_1_2_1_11_2","first-page":"175","article-title":"1958 revision of diagnostic criteria for rheumatoid arthritis","volume":"9","author":"Ropes MW","year":"1958","journal-title":"Bull Rheum Dis"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(72)90064-2"},{"key":"e_1_2_1_13_2","volume-title":"Mammals classification, The World of Mammals","author":"Simpson GG","year":"1977"},{"key":"e_1_2_1_14_2","first-page":"603","article-title":"Studies of antinuclear antibodies in rheumatoid arthritis","volume":"9","author":"Garc\u00eda\u2010de la Torre I","year":"1982","journal-title":"J Rheumatol"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI108007"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780230802"},{"key":"e_1_2_1_17_2","volume-title":"Ammonium sulfate precipitation, Methods in Immunology","author":"Garvey JS","year":"1977"},{"key":"e_1_2_1_18_2","volume-title":"Polymyositis, Clinical Immunology","author":"Messner RP","year":"1980"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-197707000-00001"},{"key":"e_1_2_1_20_2","first-page":"591","article-title":"Seroreactivity in myositis patients","volume":"11","author":"Reichlin M","year":"1984","journal-title":"J Rheumatol"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197806012982215"},{"key":"e_1_2_1_22_2","first-page":"728","article-title":"Immunogenetic studies of juvenile dermatomyositis: increased occurrence of HLA\u2010B8, DRw\u20103 and their relation to PM\u20101 and other autoantibodies (abstract)","volume":"23","author":"Pachman LM","year":"1980","journal-title":"Arthritis Rheum"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/0198-8859(81)90055-0"},{"key":"e_1_2_1_24_2","first-page":"925","article-title":"The Jo\u20101 antibody system in myositis: relationship to clinical features and HLA","volume":"8","author":"Arnett FC","year":"1981","journal-title":"J Rheumatol"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1038\/304177a0"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.160.2.420"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4612-5250-4"}],"container-title":["Arthritis &amp; 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