{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:20:35Z","timestamp":1760188835818},"reference-count":12,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,12,9]],"date-time":"2005-12-09T00:00:00Z","timestamp":1134086400000},"content-version":"vor","delay-in-days":5060,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis &amp; Rheumatism"],"published-print":{"date-parts":[[1992,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Objective.<\/jats:italic> To explore alterations in energy utilization as a potential etiology for weakness in polymyositis and dermatomyositis (PM\/DM).<\/jats:p><jats:p><jats:italic>Methods.<\/jats:italic> P\u201031 magnetic resonance spectroscopy studies were performed in patients with acute and treated PM\/DM and in normal controls, at rest and with exercise.<\/jats:p><jats:p><jats:italic>Results.<\/jats:italic> Patients with acute and treated PM\/DM showed increased ratios of inorganic phosphate to phosphocreatine (PCr) during exercise, with loss of ATP disproportional to loss of PCr.<\/jats:p><jats:p><jats:italic>Conclusion.<\/jats:italic> This study demonstrates changes in energy utilization in PM\/DM, thus supporting the notion of a metabolic etiology for the weakness associated with these diseases.<\/jats:p>","DOI":"10.1002\/art.1780350212","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T23:47:17Z","timestamp":1171496837000},"page":"199-203","source":"Crossref","is-referenced-by-count":33,"title":["P\u201031 Magnetic Resonance Spectroscopy in Polymyositis and Dermatomyositis"],"prefix":"10.1002","volume":"35","author":[{"given":"Eric D.","family":"Newman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert J.","family":"Kurland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,9]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"1401","article-title":"Relationships between clinical features and distribution of mononuclear cells in muscle of patients with polymyositis","volume":"15","author":"Kalovidouris AE","year":"1988","journal-title":"J Rheumatol"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/014107688908200607"},{"key":"e_1_2_1_4_2","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/S0033-8389(22)01078-8","article-title":"Magnetic resonance spectroscopy of the musculoskeletal system","volume":"24","author":"Burt CT","year":"1986","journal-title":"Radiol Clin North Am"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320250408"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197502132920706"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910170219"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(82)92635-6"},{"issue":"9","key":"e_1_2_1_9_2","first-page":"S22","article-title":"P\u201031 magnetic resonance spectroscopy in the evaluation of idiopathic inflammatory myopathy (abstract)","volume":"33","author":"Fraser DD","year":"1990","journal-title":"Arthritis Rheum"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.177.2.2217788"},{"issue":"4","key":"e_1_2_1_11_2","first-page":"S125","article-title":"Abnormal energy metabolism in murine polymyositis (abstract)","volume":"32","author":"Chowdhury SA","year":"1989","journal-title":"Arthritis Rheum"},{"issue":"9","key":"e_1_2_1_12_2","first-page":"S70","article-title":"Reduced transcript availability and myoadenylate deaminase (MAD) activity in polymyositis: implications for acquired MAD deficiency (abstract)","volume":"33","author":"Sabina RL","year":"1990","journal-title":"Arthritis Rheum"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.84.24.8976"}],"container-title":["Arthritis &amp; 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