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He was given parenteral magnesium and had dramatic improvement in symptoms as well as in muscle intracellular levels of this cation. After cessation of magnesium therapy the symptoms recurred, and magnesium repletion again led to an improvement in symptoms and ATP levels. Low tissue levels of magnesium, even in the setting of normal serum levels, may lead to the neuromuscular symptoms in EMS and related disorders.<\/jats:p>","DOI":"10.1002\/art.1780370910","type":"journal-article","created":{"date-parts":[[2007,2,15]],"date-time":"2007-02-15T01:11:19Z","timestamp":1171501879000},"page":"1331-1334","source":"Crossref","is-referenced-by-count":12,"title":["Magnesium deficiency in the eosinophilia\u2014myalgia syndrome. report of clinical and biochemical improvement with repletion"],"prefix":"10.1002","volume":"37","author":[{"given":"Daniel J.","family":"Clauw","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathleen","family":"Ward","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beverly","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Katz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunder S.","family":"Rajan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,9]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.263.11.1502"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-113-2-124"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(90)90421-Z"},{"key":"e_1_2_1_5_2","first-page":"867","article-title":"The eosinophilia myalgia syndrome: the Los Alamos Conference","volume":"18","author":"Hertzman P","year":"1991","journal-title":"J Rheumatol"},{"key":"e_1_2_1_6_2","unstructured":"HertzmanP KaufmanLD LoveLA MeasePJ PhilenR PincusT RosenbergNL SilverR SternbergEM VargaJ ClauwDJ: The eosinophilia myalgia syndrome: guidelines for patient care.J Rheumatol(in press)"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-111-2-143"},{"key":"e_1_2_1_8_2","first-page":"654","article-title":"P\u201031 magnestic resonance spectroscopy of skeletal muscle in the eosinophilia myalgia syndrome: a preliminary study","volume":"21","author":"Clauw DJ","year":"1994","journal-title":"J Rheumatol"},{"key":"e_1_2_1_9_2","first-page":"1600","article-title":"31\u2010P magnetic resonance spectroscopy of skeletal muscle in patients with fibromyalgia","volume":"19","author":"Jacobsen S","year":"1992","journal-title":"J Rheumatol"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.177.2.2217788"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-196901000-00003"},{"key":"e_1_2_1_12_2","first-page":"172","article-title":"Laboratory tests for the assessment of magnesium status in humans","volume":"10","author":"Elin RJ","year":"1992","journal-title":"Magnes Trace Elem"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780350308"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(90)91375-G"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910240117"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198312083092302"},{"issue":"9","key":"e_1_2_1_17_2","first-page":"S91","article-title":"Demonstration of low tissue magnesium in eosinophilia myalgia syndrome (abstract)","volume":"36","author":"Ling SM","year":"1993","journal-title":"Arthritis Rheum"}],"container-title":["Arthritis &amp; Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fart.1780370910","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/art.1780370910","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T19:30:48Z","timestamp":1700767848000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/art.1780370910"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,8]]},"references-count":16,"journal-issue":{"issue":"9","published-print":{"date-parts":[[1994,8]]}},"alternative-id":["10.1002\/art.1780370910"],"URL":"https:\/\/doi.org\/10.1002\/art.1780370910","archive":["Portico"],"relation":{},"ISSN":["0004-3591","1529-0131"],"issn-type":[{"value":"0004-3591","type":"print"},{"value":"1529-0131","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,8]]}}}