{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T09:41:42Z","timestamp":1780652502812,"version":"3.54.1"},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,12,12]],"date-time":"2005-12-12T00:00:00Z","timestamp":1134345600000},"content-version":"vor","delay-in-days":3602,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis &amp; Rheumatism"],"published-print":{"date-parts":[[1996,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Objective<\/jats:italic>. To ascertain the frequency of polymyalgia rheumatica (PMR) with a normal erythrocyte sedimentation rate (ESR; \u226430 mm\/hour) and to determine any defining clinical characteristics.<\/jats:p><jats:p><jats:italic>Methods<\/jats:italic>. A retrospective chart review study of all patients meeting the clinical criteria for PMR seen over a 5\u2010year period in a hospital and an office\u2010based rheumatology practice.<\/jats:p><jats:p><jats:italic>Results<\/jats:italic>. We evaluated 117 patients; 26 (22.2%) had a pretreatment ESR of \u2a7d30 mm\/hour (mean \u00b1 SD 19.8 \u00b1 7.5 versus 74.4 \u00b1 30.3 mm\/hour for elevated ESR group; <jats:italic>P<\/jats:italic> &lt; 0.0001). Of the 26 normal ESR patients, 15 (58%) were female compared with 74 of the 91 elevated ESR patients (81%) (<jats:italic>P<\/jats:italic> &lt; 0.02, by Fisher's exact test). The mean hemoglobin concentration was significantly lower in the elevated ESR population (mean \u00b1 SD 1.23 \u00b1 0.15 gm\/liter versus 1.38 \u00b1 0.11 gm\/liter; <jats:italic>P<\/jats:italic> &lt; 0.0001). The duration of symptoms prior to treatment with prednisone was significantly longer for patients with a normal ESR (149 \u00b1 95 days versus 103 \u00b1 95 days for elevated ESR patients; <jats:italic>P<\/jats:italic> &lt;0.04).<\/jats:p><jats:p><jats:italic>Conclusion<\/jats:italic>. In our series, PMR with a normal ESR accounted for approximately one\u2010fifth of all PMR patients, more commonly in men. The lack of characteristically abnormal laboratory findings may result in a delay in the proper diagnosis and management of this condition.<\/jats:p>","DOI":"10.1002\/art.1780390220","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T11:47:58Z","timestamp":1171453678000},"page":"304-307","source":"Crossref","is-referenced-by-count":57,"title":["Polymyalgia rheumatica in patients with a normal erythrocyte sedimentation rate"],"prefix":"10.1002","volume":"39","author":[{"given":"Simon M.","family":"Helfgott","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raphael I.","family":"Kieval","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,12,12]]},"reference":[{"key":"e_1_2_1_2_2","volume-title":"Textbook of Rheumatology","author":"Hunder GG","year":"1989"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-97-5-672"},{"key":"e_1_2_1_4_2","first-page":"309","article-title":"Polymyalgia rheumatica: duration of therapy and long\u2010term outcome","volume":"79","author":"Ayoub WT","year":"1985","journal-title":"Ann Intern Med"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.48.8.667"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-197101000-00001"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.40.1.1"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.42.2.168"},{"key":"e_1_2_1_9_2","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/S0889-857X(21)01061-9","article-title":"Polymyalgia rheumatica","volume":"16","author":"Cohen MD","year":"1990","journal-title":"Rheum Dis Clin North Am"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5544.85"},{"issue":"9","key":"e_1_2_1_11_2","first-page":"S410","article-title":"Polymyalgia rheumatica without clinically significant increased ESR (abstract)","volume":"37","author":"Sueiro JLF","year":"1994","journal-title":"Arthritis Rheum"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-104-4-515"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780341215"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-121-7-199410010-00003"},{"key":"e_1_2_1_15_2","first-page":"627","article-title":"CD8+ lymphocyte subset in polymyalgia rheumatica and arteritis temporalis: inverse relationship between the acute hepatic phase reactants and the CD8+ T\u2010cell subset","volume":"7","author":"Elling H","year":"1989","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_1_16_2","first-page":"1","article-title":"Is seronegative rheumatoid arthritis in the elderly the same as polymyalgia rheumatica?","volume":"43","author":"Hunder GG","year":"1994","journal-title":"Bull Rheum Dis"}],"container-title":["Arthritis &amp; Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fart.1780390220","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/art.1780390220","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T23:46:41Z","timestamp":1700696801000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/art.1780390220"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,2]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1996,2]]}},"alternative-id":["10.1002\/art.1780390220"],"URL":"https:\/\/doi.org\/10.1002\/art.1780390220","archive":["Portico"],"relation":{},"ISSN":["0004-3591","1529-0131"],"issn-type":[{"value":"0004-3591","type":"print"},{"value":"1529-0131","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,2]]}}}