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In both cases, the lymphoma was undetectable several weeks after diagnostic biopsy followed by discontinuation of MTX. These observations suggest that, in patients with RA who develop an EBV\u2010associated lymphoproliferative disorder, a trial of discontinuation of immunosuppressive agents may be warranted before chemotherapy is considered. In addition, there is a need for a heightened awareness of the development of lymphoma in this patient population.<\/jats:p>","DOI":"10.1002\/art.1780390223","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T11:47:58Z","timestamp":1171453678000},"page":"325-329","source":"Crossref","is-referenced-by-count":70,"title":["Methotrexate\u2010associated lymphoma in patients with rheumatoid arthritis. 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