{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:20:54Z","timestamp":1760188854016},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,12,12]],"date-time":"2005-12-12T00:00:00Z","timestamp":1134345600000},"content-version":"vor","delay-in-days":3542,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis &amp; Rheumatism"],"published-print":{"date-parts":[[1996,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report the unusual case of a man with a 5\u2010year history of relapsing Henoch\u2010Sch\u00f6nlein purpura (HSP) and macroscopic polyarteritis nodosa (PAN) as early manifestations of IgA\u03ba multiple myeloma. The glomeruli contained monoclonal IgA\u03ba deposits, without other immunoglobulins or \u03bb light chains. Glomerular deposits lacked the usual electron density but could be demonstrated by immunoelectron microscopy. Multisystem large vessel vasculitis (antineutrophil cytoplasmic antibody negative) produced aneurysms of renal and hepatic arteries, whereas small vessel vasculitis affected the skin and glomeruli, producing a symptom complex of HSP with dermal and glomerular deposits of IgA. We conclude that HSP\/overlap syndrome may be the initial manifestation of IgA myeloma and should be considered within the spectrum of monoclonal IgA deposition disease.<\/jats:p>","DOI":"10.1002\/art.1780390425","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T11:40:22Z","timestamp":1171453222000},"page":"698-703","source":"Crossref","is-referenced-by-count":38,"title":["IgA multiple myeloma presenting as Henoch\u2010Sch\u00f6nlein purpura\/polyarteritis nodosa overlap syndrome"],"prefix":"10.1002","volume":"39","author":[{"given":"Daniel","family":"Birchmore","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Sweeney","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Devasmita","family":"Choudhury","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin F.","family":"Konwinski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin","family":"Carnevale","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivette","family":"D'Agati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,12]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(88)80028-3"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(80)80011-8"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(12)70306-2"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1159\/000181970"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-118-10-199305150-00021"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(12)60015-9"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(86)90186-5"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI112522"},{"key":"e_1_2_1_10_2","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1159\/000463206","article-title":"Immunoglobulin A: interaction with complement, phagocytic cells and endothelial cells","volume":"8","author":"Bogers WMJM","year":"1991","journal-title":"Complement Inflamm"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0019-2791(76)90195-6"},{"key":"e_1_2_1_12_2","first-page":"335","article-title":"Glomerular deposition and serum levels of complement control proteins in patients with IgA nephropathy","volume":"21","author":"Miyazaki R","year":"1984","journal-title":"Clin Nephrol"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.150.5.1161"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199311043291913"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780351121"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-105-5-709"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(86)70222-3"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.61.715.445"},{"key":"e_1_2_1_19_2","first-page":"168","article-title":"Polyarteritis nodosa associated with biclonal gammopathy of two cell line origin and amyloidosis","volume":"12","author":"Bouvet J\u2010P","year":"1985","journal-title":"J Rheumatol"}],"container-title":["Arthritis &amp; Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fart.1780390425","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/art.1780390425","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T02:02:25Z","timestamp":1700704945000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/art.1780390425"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,4]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1996,4]]}},"alternative-id":["10.1002\/art.1780390425"],"URL":"https:\/\/doi.org\/10.1002\/art.1780390425","archive":["Portico"],"relation":{},"ISSN":["0004-3591","1529-0131"],"issn-type":[{"value":"0004-3591","type":"print"},{"value":"1529-0131","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,4]]}}}