{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T10:18:13Z","timestamp":1780654693760,"version":"3.54.1"},"reference-count":15,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2005,12,12]],"date-time":"2005-12-12T00:00:00Z","timestamp":1134345600000},"content-version":"vor","delay-in-days":3420,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis &amp; Rheumatism"],"published-print":{"date-parts":[[1996,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Objective<\/jats:italic>. To evaluate the utility of computed tomography (CT) of the knee joint for detecting intraarticular tophaceous deposits.<\/jats:p><jats:p><jats:italic>Methods<\/jats:italic>. A prospective study of 16 patients with gout affecting the knee was conducted. A condition for inclusion in the study was the presence of needle\u2010shaped crystals with negative birefringence in the knee joint synovial fluid. Conventional radiography and CT were performed in each case.<\/jats:p><jats:p><jats:italic>Results<\/jats:italic>. Intraarticular opacities in the capsule and the synovium, consistent with the presence of tophaceous deposits, were found in 5 of the 16 patients (9 knee joints). The mean duration of gout was longer in the patients with intraarticular tophi than in those without tophi, and 2 of the patients with tophi had poor tolerance to antihyperuricemic therapy.<\/jats:p><jats:p><jats:italic>Conclusion<\/jats:italic>. Intraarticular opacities considered to represent tophi were observed in approximately one\u2010third of the patients. The presence of tophi correlated with a longer duration of the disease and a poor tolerance to medication. We therefore suggest that CT of the knees could be useful in the assessment and followup of certain patients with gout.<\/jats:p>","DOI":"10.1002\/art.1780390820","type":"journal-article","created":{"date-parts":[[2007,2,14]],"date-time":"2007-02-14T12:02:15Z","timestamp":1171454535000},"page":"1406-1409","source":"Crossref","is-referenced-by-count":63,"title":["Computed tomography of the knee joint as an indicator of intraarticular tophi in gout"],"prefix":"10.1002","volume":"39","author":[{"given":"Jean C.","family":"Gerster","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Landry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertrand","family":"Duvoisin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georges","family":"Rappoport","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,12,12]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780270417"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780200320"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.181.2.1789832"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.54.6.516"},{"key":"e_1_2_1_6_2","volume-title":"Diagnosis of Bone and Joint Disorders","author":"Resnick D","year":"1995"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0049-0172(84)90016-7"},{"key":"e_1_2_1_8_2","volume-title":"Rheumatology","author":"Cohen MG","year":"1994"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00193819"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198908033210504"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780340203"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.54.2.79"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780341203"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0266-7681(88)90049-6"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.40.4.416"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199505000-00013"}],"container-title":["Arthritis &amp; Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fart.1780390820","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/art.1780390820","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T03:48:46Z","timestamp":1698724126000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/art.1780390820"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,8]]},"references-count":15,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1996,8]]}},"alternative-id":["10.1002\/art.1780390820"],"URL":"https:\/\/doi.org\/10.1002\/art.1780390820","archive":["Portico"],"relation":{},"ISSN":["0004-3591","1529-0131"],"issn-type":[{"value":"0004-3591","type":"print"},{"value":"1529-0131","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,8]]}}}