{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T22:35:04Z","timestamp":1778538904491,"version":"3.51.4"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,2,6]],"date-time":"2006-02-06T00:00:00Z","timestamp":1139184000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis &amp; Rheumatism"],"published-print":{"date-parts":[[2006,2,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To examine patterns of chronic opioid use in selected groups with arthritis and low back pain and compare them with patterns among persons with ischemic heart disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study database consisted of Medicare beneficiaries who were enrolled in a drug benefit program for low\u2010to\u2010moderate income Pennsylvania residents. We identified selected patients who had a diagnosis of rheumatoid arthritis, osteoarthritis, chronic low back pain, or ischemic heart disease since 1995. Chronic opioid use, defined as at least six 30\u2010day prescriptions in a year, was the endpoint of interest. We examined the proportion of patients meeting this definition during the period 1996\u20132001 and determined predictors based on multivariable Cox proportional hazards models.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Four percent of subjects with rheumatoid arthritis used opioids chronically in 2001, compared with &lt;1% in each of the other groups. There was no increase in the chronic use of opioids over the 6\u2010year study period. Low\u2010potency opioids were the most commonly prescribed preparations for chronic users from all patient groups. The prior use of medicines for psychiatric illness, including benzodiazepines or barbiturates, was associated with chronic prescription opioid use across all diagnoses. However, subjects with a prior diagnosis of psychiatric illness were less likely to receive chronic opioids.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Chronic opioid use is relatively uncommon, even among older individuals with arthritis or low back pain. The proportion of these individuals receiving such medicines has not increased in the late 1990s. There seems to be a complex relationship between psychiatric medication use, psychiatric diagnoses, and the use of chronic opioids among these individuals.<\/jats:p><\/jats:sec>","DOI":"10.1002\/art.21697","type":"journal-article","created":{"date-parts":[[2006,2,6]],"date-time":"2006-02-06T23:46:57Z","timestamp":1139269617000},"page":"35-41","source":"Crossref","is-referenced-by-count":51,"title":["Prescription opioid use among older adults with arthritis or low back pain"],"prefix":"10.1002","volume":"55","author":[{"given":"Daniel H.","family":"Solomon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerry","family":"Avorn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip S.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Vaillant","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle","family":"Cabral","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen","family":"Mogun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Til","family":"St\u00fcrmer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,2,6]]},"reference":[{"key":"e_1_2_5_2_2","volume-title":"Healthy people 2010","author":"Centers for Disease Control and Prevention","year":"2000"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(199805)41:5<778::AID-ART4>3.0.CO;2-V"},{"key":"e_1_2_5_4_2","unstructured":"American Pain Society. Promoting pain relief and preventing abuse of pain medications: a critical balancing act a joint statement from 21 health organizations and the Drug Enforcement Administration. URL:http:\/\/www.ampainsoc.org\/advocacy\/promoting.htm."},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200009)43:9<1905::AID-ANR1>3.0.CO;2-P"},{"key":"e_1_2_5_6_2","volume-title":"Guideline for the management of pain in osteoarthritis, rheumatoid arthritis and juvenile chronic arthritis","author":"Arthritis Pain Guideline Panel of the American Pain Society","year":"2002"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.164.21.2361"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2004.03.006"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/pds.755"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(199809)41:9<1603::AID-ART10>3.0.CO;2-U"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1790060409"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2004.02.019"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-7125(05)70133-4"},{"key":"e_1_2_5_14_2","volume-title":"Goodman and Gilman's pharmacological basis of therapeutics","author":"Reisine T","year":"1996"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(92)90133-8"}],"container-title":["Arthritis Care &amp; Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fart.21697","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/art.21697","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T23:37:52Z","timestamp":1697153872000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/art.21697"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,2,6]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,2,15]]}},"alternative-id":["10.1002\/art.21697"],"URL":"https:\/\/doi.org\/10.1002\/art.21697","archive":["Portico"],"relation":{},"ISSN":["0893-7524","1529-0123"],"issn-type":[{"value":"0893-7524","type":"print"},{"value":"1529-0123","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,2,6]]}}}