{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T21:27:41Z","timestamp":1771104461993,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,12,28]],"date-time":"2006-12-28T00:00:00Z","timestamp":1167264000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis &amp; Rheumatism"],"published-print":{"date-parts":[[2007,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To estimate the incidence and prevalence of Ro\/SSA\u2010positive subacute cutaneous lupus erythematosus (SCLE) in Stockholm County, Sweden (1.8 million inhabitants) and to investigate the frequency of photosensitivity and other clinical manifestations associated with Ro\/SSA autoantibodies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Ro\/SSA\u2010positive patients in Stockholm were identified via registry\u2010based searches. All patients who tested positive for the presence of Ro\/SSA autoantibodies during 1996\u20132002 (n = 1,323; 85% women) were identified. A questionnaire was sent to all patients still living in Stockholm in 2003 (n = 1,048). Patients who reported having skin symptoms and photosensitivity (n = 125) underwent a clinical examination.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 741 (71%) of 1,048 Ro\/SSA\u2010positive patients who responded to the questionnaire, 400 (54%) reported having photosensitivity, and of these patients, 125 agreed to be clinically examined. A diagnosis of LE was confirmed in 59 of the 125 patients (SCLE in 20, systemic LE [SLE] in 33, and chronic CLE in 6). Eighty\u2010six patients reported experiencing symptoms consistent with polymorphous light eruption (PLE). Comorbidities such as cardiovascular disease, autoimmune disease, and other skin diseases were common. The incidence of Ro\/SSA\u2010positive SCLE during the study period was estimated to be 0.7 cases per 100,000 persons per year and the prevalence was \u223c6.2\u201314 in 100,000 persons.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The incidence of Ro\/SSA\u2010positive SCLE in Stockholm County, Sweden is estimated to be 0.7 per 100,000 persons per year as compared with an incidence of SLE in Sweden of 4.8 per 100,000 persons per year. The prevalence is estimated to be 6.2\u201314 in 100,000 persons. Self\u2010reported photosensitivity commonly corresponds to a history of PLE in Ro\/SSA\u2010positive patients, even when the clinical profile of SCLE is absent. Photoprotection should therefore be included in the treatment recommendations for these patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/art.22286","type":"journal-article","created":{"date-parts":[[2006,12,29]],"date-time":"2006-12-29T00:48:53Z","timestamp":1167353333000},"page":"255-264","source":"Crossref","is-referenced-by-count":49,"title":["A serology\u2010based approach combined with clinical examination of 125 Ro\/SSA\u2010positive patients to define incidence and prevalence of subacute cutaneous lupus erythematosus"],"prefix":"10.1002","volume":"56","author":[{"given":"Karin","family":"Popovic","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fredrik","family":"Nyberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie","family":"Wahren\u2010Herlenius","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filippa","family":"Nyberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,1,2]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1979.04010120007006"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780310811"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780251101"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(81)80261-7"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-97-5-664"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(98)70497-9"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1994.01690100046006"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.139.1.45"},{"key":"e_1_2_7_10_2","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1046\/j.1365-2133.1997.d01-1172.x","article-title":"Occurrence of polymorphous light eruption in lupus erythematosus","volume":"136","author":"Nyberg F","year":"1997","journal-title":"Br J Dermatol"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2001.04339.x"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.61.6.554"},{"key":"e_1_2_7_13_2","first-page":"2345","article-title":"Undifferentiated connective tissue disease: analysis of 83 patients with a minimum followup of 5 years","volume":"29","author":"Mosca M","year":"2002","journal-title":"J Rheumatol"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/096120339700600204"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0090-1229(85)90045-5"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/24.2.147"},{"key":"e_1_2_7_17_2","first-page":"43","volume-title":"Modern epidemiology","author":"Rothman, Greenland","year":"1998"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-7125(16)30620-4"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.1987.tb00108.x"},{"key":"e_1_2_7_20_2","first-page":"298","article-title":"Current aspects of polymorphous light eruptions in Sweden","volume":"3","author":"Ros AM","year":"1986","journal-title":"Photodermatol"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1994.tb06884.x"},{"key":"e_1_2_7_22_2","first-page":"632","article-title":"Cutaneous manifestations of primary Sjogren's syndrome are underestimated","volume":"22","author":"Roguedas AM","year":"2004","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1087-0024.2004.00839.x"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1191\/096120301678416024"},{"key":"e_1_2_7_25_2","first-page":"102","volume-title":"Photodermatology","author":"Norris P","year":"1998"},{"key":"e_1_2_7_26_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2002.04640.x"},{"key":"e_1_2_7_27_2","doi-asserted-by":"publisher","DOI":"10.1080\/rhe.31.3.133.139"},{"key":"e_1_2_7_28_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-199505000-00001"},{"key":"e_1_2_7_29_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1998.02278.x"},{"key":"e_1_2_7_30_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1983.tb03553.x"}],"container-title":["Arthritis &amp; 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