{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T07:37:32Z","timestamp":1780472252442,"version":"3.54.1"},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2007,3,28]],"date-time":"2007-03-28T00:00:00Z","timestamp":1175040000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis &amp; Rheumatism"],"published-print":{"date-parts":[[2007,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This is the first report of a <jats:italic>CARD15<\/jats:italic> mutation\u2013positive patient with Blau syndrome who exhibited interstitial lung disease, a feature historically considered absent from Blau syndrome, while typical of the adult form of sarcoidosis. This case illustrates the continued evolution of the phenotype of a disease initially conceived as a familial inflammatory granulomatous disease limited to the triad of synovitis, dermatitis, and uveitis.<\/jats:p>","DOI":"10.1002\/art.22509","type":"journal-article","created":{"date-parts":[[2007,3,28]],"date-time":"2007-03-28T17:47:25Z","timestamp":1175104045000},"page":"1292-1294","source":"Crossref","is-referenced-by-count":57,"title":["Interstitial pneumonitis in Blau syndrome with documented mutation in <i>CARD15<\/i>"],"prefix":"10.1002","volume":"56","author":[{"given":"Mara L.","family":"Becker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tammy M.","family":"Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trudy M.","family":"Doyle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos D.","family":"Ros\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,3,28]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(85)80394-2"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(85)90286-4"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198201143060208"},{"key":"e_1_2_5_5_2","first-page":"396","article-title":"Liver involvement in familial granulomatous arthritis (Blau syndrome)","volume":"23","author":"Saini SK","year":"1996","journal-title":"J Rheumatol"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(98)70286-0"},{"key":"e_1_2_5_7_2","first-page":"1097","article-title":"Genetic linkage of familial granulomatous inflammatory arthritis, skin rash, and uveitis to chromosome 16","volume":"59","author":"Tromp G","year":"1996","journal-title":"Am J Hum Genet"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng720"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0022-202X.2004.22341.x"},{"key":"e_1_2_5_10_2","first-page":"373","article-title":"Blau syndrome mutation of CARD15\/NOD2 in sporadic early onset granulomatous arthritis","volume":"32","author":"Rose CD","year":"2005","journal-title":"J Rheumatol"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.03.00040602"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.22122"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(02)01709-9"},{"key":"e_1_2_5_14_2","first-page":"174","article-title":"Early onset sarcoidosis: not a benign disease","volume":"24","author":"Fink CW","year":"1997","journal-title":"J Rheumatol"},{"key":"e_1_2_5_15_2","first-page":"685","article-title":"Sarcoidosis of early onset: a challenge for the pediatric rheumatologist","volume":"11","author":"Hafner R","year":"1993","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.10618"}],"container-title":["Arthritis &amp; Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fart.22509","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/art.22509","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T23:41:18Z","timestamp":1698709278000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/art.22509"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3,28]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,4]]}},"alternative-id":["10.1002\/art.22509"],"URL":"https:\/\/doi.org\/10.1002\/art.22509","archive":["Portico"],"relation":{},"ISSN":["0004-3591","1529-0131"],"issn-type":[{"value":"0004-3591","type":"print"},{"value":"1529-0131","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,3,28]]}}}