{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T20:50:29Z","timestamp":1784062229491,"version":"3.55.0"},"reference-count":43,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2007,12,28]],"date-time":"2007-12-28T00:00:00Z","timestamp":1198800000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis &amp; Rheumatism"],"published-print":{"date-parts":[[2008,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the basic 8\u2010week People with Arthritis Can Exercise (PACE) program for improvements in primary (symptoms, functioning, level of physical activity) and secondary (psychosocial) outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 346 individuals with self\u2010reported arthritis from 18 sites participated in a randomized controlled trial of PACE. Outcomes were measured at baseline and 8 weeks. The intervention group completed self\u2010reported assessments at 3 and 6 months. Two\u2010level multiple linear regression models were estimated to calculate adjusted outcome means in the intervention and control groups. A mixed\u2010effects repeated\u2010measures model was used to calculate adjusted means in the intervention group at 3 and 6 months. Both intent\u2010to\u2010treat (ITT) and as\u2010treated (AT) analyses were conducted.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At 8 weeks, the intervention group had improvements in the following outcomes: 2 symptom outcomes (pain, fatigue) and 1 psychosocial outcome (self\u2010efficacy for managing arthritis) in the ITT analyses; 1 symptom outcome (pain), 1 function outcome (chair stands), and 1 psychosocial outcome (self\u2010efficacy for arthritis management) in the AT analyses. In addition, completers who attended \u22659 classes had improvements in 3 symptom outcomes (pain, fatigue, stiffness), 2 function outcomes (10\u2010pound lifts, chair stands), and 1 psychosocial outcome (self\u2010efficacy for arthritis management) at 8 weeks. Relative to baseline, PACE participants maintained significant improvements in symptoms at 6 months, but declined in function and self\u2010efficacy for exercise.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>If adults with arthritis attend a majority of PACE classes, they may expect improvements in symptoms, self\u2010efficacy for arthritis management, and upper and lower extremity function. Achieving sustained improvement in outcomes may require continued participation in PACE.<\/jats:p><\/jats:sec>","DOI":"10.1002\/art.23239","type":"journal-article","created":{"date-parts":[[2007,12,28]],"date-time":"2007-12-28T18:18:34Z","timestamp":1198865914000},"page":"92-101","source":"Crossref","is-referenced-by-count":81,"title":["A randomized controlled trial of the people with arthritis can exercise program: Symptoms, function, physical activity, and psychosocial outcomes"],"prefix":"10.1002","volume":"59","author":[{"given":"Leigh 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