{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T18:02:52Z","timestamp":1788631372663,"version":"build-2803163510"},"reference-count":47,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2009,5,28]],"date-time":"2009-05-28T00:00:00Z","timestamp":1243468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis &amp; Rheumatism"],"published-print":{"date-parts":[[2009,6,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the risk of radiographic knee osteoarthritis (OA) and lumbar spondylosis associated with occupational activity in elderly Japanese subjects using the large\u2010scale population\u2010based cohort of the Research on Osteoarthritis Against Disability (ROAD) study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>From the baseline survey of the ROAD study, 1,471 participants age \u226550 years (531 men and 940 women) living in mountainous and seacoast communities were analyzed. Information collected included a lifetime occupational history and details of specific work place physical activities. Radiographic severity at the knee and lumbar spine was determined by the Kellgren\/Lawrence (K\/L) grading system.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The prevalence of K\/L grade \u22652 knee OA and lumbar spondylosis among agricultural, forestry, and fishery workers was significantly higher than among clerical workers and technical experts in the overall population. For occupational activities, sitting on a chair had a significant inverse association with K\/L grade \u22652 knee OA and lumbar spondylosis. Standing, walking, climbing, and heavy lifting were associated with K\/L grade \u22652 knee OA, but were not associated with K\/L grade \u22652 lumbar spondylosis. Kneeling and squatting were associated with K\/L grade \u22653 knee OA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This cross\u2010sectional study using a population\u2010based cohort suggests that sitting on a chair is a significant protective factor against both radiographic knee OA and lumbar spondylosis in Japanese subjects. An occupational activity that includes heavy lifting appears to have a greater effect on knee OA than on lumbar spondylosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/art.24514","type":"journal-article","created":{"date-parts":[[2009,5,28]],"date-time":"2009-05-28T16:07:42Z","timestamp":1243526862000},"page":"779-786","source":"Crossref","is-referenced-by-count":78,"title":["Association of occupational activity with radiographic knee osteoarthritis and lumbar spondylosis in elderly patients of population\u2010based cohorts: A large\u2010scale population\u2010based study"],"prefix":"10.1002","volume":"61","author":[{"given":"Shigeyuki","family":"Muraki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toru","family":"Akune","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Oka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiko","family":"Mabuchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshio","family":"En\u2010Yo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Munehito","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiko","family":"Saika","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kozo","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Kawaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriko","family":"Yoshimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,5,28]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-200110001-00003"},{"issue":"1","key":"e_1_2_6_3_2","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1093\/rheumatology\/41.S1.3","article-title":"The prevalence and burden of arthritis","volume":"41","author":"Reginster JY","year":"2002","journal-title":"Rheumatology (Oxford)"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.blo.0000143938.30681.9d"},{"key":"e_1_2_6_5_2","first-page":"3","volume-title":"Osteoarthritis: diagnosis and medical\/surgical management","author":"Sharma L","year":"2007"},{"key":"e_1_2_6_6_2","first-page":"561","article-title":"Pathomechanics and clinical relevance of disc degeneration and annular tear: a point\u2010of\u2010view review","volume":"28","author":"Hadjipavlou AG","year":"1999","journal-title":"Am J Orthop"},{"key":"e_1_2_6_7_2","first-page":"427","volume-title":"Osteoarthritis: diagnosis and medical\/surgical management","author":"Emery SE","year":"2007"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5604.525"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.30B4.664"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.3109\/17453677708989742"},{"key":"e_1_2_6_11_2","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1097\/00003086-199210000-00029","article-title":"The long\u2010term course of various meniscal treatments in anterior cruciate ligament deficient knees","volume":"283","author":"Sommerlath K","year":"1992","journal-title":"Clin Orthop Relat Res"},{"key":"e_1_2_6_12_2","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1302\/0301-620X.75B1.8421030","article-title":"Results of partial meniscectomy related to the state of the anterior cruciate ligament: review at 20 to 35 years","volume":"75","author":"Neyret P","year":"1993","journal-title":"J Bone Joint Surg Br"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.epirev.a036019"},{"key":"e_1_2_6_14_2","first-page":"197","article-title":"Rheumatism in miners. II. X\u2010ray study","volume":"9","author":"Kellgren JH","year":"1952","journal-title":"Br J Ind Med"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.27.6.559"},{"key":"e_1_2_6_16_2","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1097\/00003086-198701000-00034","article-title":"Heavy labor and the occurrence of gonarthrosis","volume":"214","author":"Lindberg H","year":"1987","journal-title":"Clin Orthop Relat Res"},{"key":"e_1_2_6_17_2","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1097\/00003086-199012000-00028","article-title":"Risk factors for the development of osteoarthrosis of the knee","volume":"261","author":"Kohatsu ND","year":"1990","journal-title":"Clin Orthop Relat Res"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/20.4.1025"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1177\/140349489202000107"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a114939"},{"key":"e_1_2_6_21_2","first-page":"1587","article-title":"Occupational physical demands, knee bending, and knee osteoarthritis: results from the Framingham study","volume":"18","author":"Felson DT","year":"1991","journal-title":"J Rheumatol"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.53.2.90"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200007)43:7<1443::AID-ANR5>3.0.CO;2-1"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.505"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.643"},{"key":"e_1_2_6_26_2","first-page":"842","article-title":"The distribution, determinants, and clinical correlates of vertebral osteophytosis: a population based survey","volume":"26","author":"O'Neill TW","year":"1999","journal-title":"J Rheumatol"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.28.2.121"},{"key":"e_1_2_6_28_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-198506000-00008"},{"key":"e_1_2_6_29_2","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1097\/00007632-199008000-00002","article-title":"Lumbar spinal pathology in cadaveric material in relation to history of back pain, occupation, and physical loading","volume":"15","author":"Videman T","year":"1990","journal-title":"Spine"},{"key":"e_1_2_6_30_2","first-page":"465","article-title":"Establishment of large\u2010scale population based cohort for prevention of osteoarthritis: the ROAD study","volume":"39","author":"Yoshimura N","year":"2008","journal-title":"Ryumachi"},{"key":"e_1_2_6_31_2","volume-title":"The epidemiology of chronic rheumatism: atlas of standard radiographs of arthritis","author":"Kellgren JH","year":"1963"},{"key":"e_1_2_6_32_2","doi-asserted-by":"publisher","DOI":"10.1136\/oem.2005.020057"},{"key":"e_1_2_6_33_2","doi-asserted-by":"publisher","DOI":"10.1093\/occmed\/52.8.441"},{"key":"e_1_2_6_34_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-133-8-200010170-00016"},{"key":"e_1_2_6_35_2","first-page":"157","article-title":"Risk factors for knee osteoarthritis in Japanese women: heavy weight, previous joint injuries, and occupational activities","volume":"31","author":"Yoshimura N","year":"2004","journal-title":"J Rheumatol"},{"key":"e_1_2_6_36_2","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/152.9.855"},{"key":"e_1_2_6_37_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002060-200105000-00002"},{"key":"e_1_2_6_38_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.52.4.258"},{"key":"e_1_2_6_39_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.57.10.588"},{"key":"e_1_2_6_40_2","first-page":"461","article-title":"The risk of osteoarthritis with running and aging: a 5\u2010year longitudinal study","volume":"20","author":"Lane NE","year":"1993","journal-title":"J Rheumatol"},{"key":"e_1_2_6_41_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.11321"},{"key":"e_1_2_6_42_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780300811"},{"key":"e_1_2_6_43_2","first-page":"429","article-title":"Epidemiology of chronic disc degeneration and osteoarthritis of the lumbar spine in Britain and Japan: a comparative study","volume":"27","author":"Yoshimura N","year":"2000","journal-title":"J Rheumatol"},{"key":"e_1_2_6_44_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.brs.0000245854.53001.4e"},{"key":"e_1_2_6_45_2","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(199901)42:1<17::AID-ANR2>3.0.CO;2-E"},{"key":"e_1_2_6_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2003.08.010"},{"key":"e_1_2_6_47_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm1409"},{"key":"e_1_2_6_48_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.22041"}],"container-title":["Arthritis Care &amp; Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fart.24514","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/art.24514","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T17:18:13Z","timestamp":1696612693000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/art.24514"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5,28]]},"references-count":47,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2009,6,15]]}},"alternative-id":["10.1002\/art.24514"],"URL":"https:\/\/doi.org\/10.1002\/art.24514","archive":["Portico"],"relation":{},"ISSN":["0893-7524","1529-0123"],"issn-type":[{"value":"0893-7524","type":"print"},{"value":"1529-0123","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,5,28]]}}}