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Ample evidence indicates that\n                    <jats:styled-content style=\"fixed-case\">GCA<\/jats:styled-content>\n                    is a heterogeneous disease in terms of symptoms, immune pathology, and response to treatment. In the current review, we discuss the evidence for disease subsets in\n                    <jats:styled-content style=\"fixed-case\">GCA<\/jats:styled-content>\n                    . We describe clinical and immunologic characteristics that may impact the risk of cranial ischemic symptoms, relapse rates, and long\u2010term glucocorticoid requirements in patients with\n                    <jats:styled-content style=\"fixed-case\">GCA<\/jats:styled-content>\n                    . In addition, we discuss both proven and putative immunologic targets for therapy in patients with\n                    <jats:styled-content style=\"fixed-case\">GCA<\/jats:styled-content>\n                    who have an unfavorable prognosis. Finally, we provide recommendations for further research on disease subsets in\n                    <jats:styled-content style=\"fixed-case\">GCA<\/jats:styled-content>\n                    .\n                  <\/jats:p>","DOI":"10.1002\/art.40520","type":"journal-article","created":{"date-parts":[[2018,4,12]],"date-time":"2018-04-12T09:58:11Z","timestamp":1523527091000},"page":"1366-1376","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":65,"title":["Review: What Is the Current Evidence for Disease Subsets in Giant Cell Arteritis?"],"prefix":"10.1002","volume":"70","author":[{"given":"Kornelis S. 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