{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T10:15:30Z","timestamp":1791195330061,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T00:00:00Z","timestamp":1778716800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T00:00:00Z","timestamp":1778716800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthritis &amp; Rheumatology"],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare the multisequence standard magnetic resonance imaging (sMRI) protocol of the sacroiliac joints with a single high\u2010resolution deep learning\u2013reconstructed Dixon sequence (DL\u2010Dixon) in patients with suspected axial spondyloarthritis (axSpA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Seventy\u2010six patients with chronic low back pain and suspected axSpA underwent clinical, laboratory, and genetic assessment followed by 3T sMRI (T1, T2 fat saturation, volumetric interpolated breath\u2010hold examination, STIR; 19:49 minutes) and high\u2010resolution DL\u2010Dixon imaging (1 mm isotropic; 5:24 minutes). Three blinded readers assessed overall imaging diagnosis, diagnostic confidence, and lesion presence (osteitis, fat metaplasia, erosions, sclerosis, joint space changes). DL was used solely for image reconstruction. The clinical diagnosis served as the reference for diagnostic accuracy; sMRI served as the reference for lesion analysis. Diagnostic accuracy was expressed as the area under the curve (AUC; balanced accuracy). Noninferiority was tested using a predefined margin of 0.05. A decrease of \u22640.05 compared to sMRI was defined as clinically acceptable.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Nineteen patients were diagnosed with axSpA. DL\u2010Dixon showed similar diagnostic performance (AUC 0.86 [95% confidence interval (CI) 0.76\u20130.96]) compared to sMRI (AUC 0.87 [95% CI 0.78\u20130.96]) and met noninferiority criteria. Interreader agreement was almost perfect for sMRI (\u03ba\u00a0=\u00a00.81) and substantial for DL\u2010Dixon (\u03ba\u00a0=\u00a00.71). At the lesion level, DL\u2010Dixon achieved good performance for erosions (AUC 0.83), fat metaplasia (AUC 0.80), and joint space changes (AUC 0.80), and fair performance for osteitis (AUC 0.73) and sclerosis (AUC 0.64). Using DL\u2010Dixon, scan time was reduced by 73%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>DL\u2010Dixon provides clinically acceptable diagnostic performance while substantially reducing scan time. This approach may improve efficiency and accessibility of MRI for axSpA assessment.<\/jats:p>\n                    <jats:p>\n                      <jats:boxed-text content-type=\"graphic\" position=\"anchor\">\n                        <jats:graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mimetype=\"image\/png\" position=\"anchor\" specific-use=\"enlarged-web-image\" xlink:href=\"graphic\/art70195-gra-0001-m.png\">\n                          <jats:alt-text>image<\/jats:alt-text>\n                        <\/jats:graphic>\n                      <\/jats:boxed-text>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/art.70195","type":"journal-article","created":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T10:13:59Z","timestamp":1776766439000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["High\u2010Resolution Deep Learning Dixon Magnetic Resonance Imaging of the Sacroiliac Joints Is Noninferior to Standard Magnetic Resonance Imaging in Patients With Suspected Axial Spondyloarthritis"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4534-0466","authenticated-orcid":false,"given":"Dominik","family":"Deppe","sequence":"first","affiliation":[{"name":"Department of Radiology Charit\u00e9\u2010Universit\u00e4tsmedizin Berlin, Campus Mitte, Humboldt\u2010Universit\u00e4t zu Berlin, Freie Universit\u00e4t Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariam","family":"Koka","sequence":"additional","affiliation":[{"name":"Department of Radiology Charit\u00e9\u2010Universit\u00e4tsmedizin Berlin, Campus Mitte, Humboldt\u2010Universit\u00e4t zu Berlin, Freie Universit\u00e4t Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4306-033X","authenticated-orcid":false,"given":"Fabian","family":"Proft","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Infectiology, and Rheumatology Charit\u00e9\u2010Universit\u00e4tsmedizin Berlin, Humboldt\u2010Universit\u00e4t zu Berlin, Freie Universit\u00e4t Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sevtap Tugce","family":"Ulas","sequence":"additional","affiliation":[{"name":"Department of Radiology Charit\u00e9\u2010Universit\u00e4tsmedizin Berlin, Campus Mitte, Humboldt\u2010Universit\u00e4t zu Berlin, Freie Universit\u00e4t Berlin  Berlin Germany"},{"name":"Department of Radiology and Biomedical Imaging University of California  San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kay\u2010Geert","family":"Hermann","sequence":"additional","affiliation":[{"name":"Department of Radiology Charit\u00e9\u2010Universit\u00e4tsmedizin Berlin, Campus Mitte, Humboldt\u2010Universit\u00e4t zu Berlin, Freie Universit\u00e4t Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4537-6015","authenticated-orcid":false,"given":"Denis","family":"Poddubnyy","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Infectiology, and Rheumatology Charit\u00e9\u2010Universit\u00e4tsmedizin Berlin, Humboldt\u2010Universit\u00e4t zu Berlin, Freie Universit\u00e4t Berlin  Berlin Germany"},{"name":"Division of Rheumatology, Department of Medicine University of Toronto and University Health Network  Toronto Ontario 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