{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T06:39:50Z","timestamp":1790404790862,"version":"4.1.0"},"reference-count":93,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2008,1,18]],"date-time":"2008-01-18T00:00:00Z","timestamp":1200614400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chemistry \u0097 An Asian Journal"],"published-print":{"date-parts":[[2008,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The catalytic acylcyanation of aldimines with acylcyanides and a direct three\u2010component variant involving the generation of an imine in\u2005situ have been developed. Furthermore, a highly enantioselective version has been established, culminating in the first organocatalytic asymmetric three\u2010component Strecker reaction. Jacobsen thiourea catalysts were found to catalyze the reaction with excellent enantioselectivities, whereas binol phosphates (binol=1,1\u2032\u2010bi\u20102,2\u2032\u2010naphthol) proved to be catalytically active but only modestly enantioselective. A large number of different substrates could be used in the processes described, thus illustrating the potential of our reaction for the generation of diversity within the attractive \u03b1\u2010amino carbonyl framework. Furthermore, a novel cyclic amidine was obtained from the reaction of acetyl cyanide with ketimines.<\/jats:p>","DOI":"10.1002\/asia.200700327","type":"journal-article","created":{"date-parts":[[2008,1,18]],"date-time":"2008-01-18T04:47:12Z","timestamp":1200631632000},"page":"430-437","source":"Crossref","is-referenced-by-count":68,"title":["The Catalytic Acylcyanation of Imines"],"prefix":"10.1002","volume":"3","author":[{"given":"Subhas\u2005Chandra","family":"Pan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"List","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,1,29]]},"reference":[{"key":"e_1_2_6_1_2","doi-asserted-by":"publisher","DOI":"10.1002\/jlac.18500750103"},{"key":"e_1_2_6_2_2","unstructured":"For reviews see:"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr020038p"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/1521-3757(20010302)113:5<900::AID-ANGE900>3.0.CO;2-#"},{"key":"e_1_2_6_4_3","doi-asserted-by":"publisher","DOI":"10.1002\/1521-3773(20010302)40:5<875::AID-ANIE875>3.0.CO;2-C"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.200301686"},{"key":"e_1_2_6_5_3","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200301686"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1039\/a908290e"},{"key":"e_1_2_6_7_2","unstructured":"\u00a0"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja980139y"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja980299"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-3757(20000403)112:7<1336::AID-ANGE1336>3.0.CO;2-Z"},{"key":"e_1_2_6_10_3","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-3773(20000403)39:7<1279::AID-ANIE1279>3.0.CO;2-U"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol005636"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja027246j"},{"key":"e_1_2_6_13_2","first-page":"1919","author":"Wenzel A. 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