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The <jats:sc>D<\/jats:sc>\u2010trihydroxyllysine derivative with three orthogonal protecting groups was conjugated with functional devices at the \u03b3\u2005position and allowed oligomerization based on peptide chemistry. The radiopharmaceutical complexes of <jats:sup>111<\/jats:sup>In<jats:sup>III<\/jats:sup> with selected chelators, <jats:bold>4<\/jats:bold> and <jats:bold>8<\/jats:bold>, were suitable for bone imaging. These results show that <jats:sc>D<\/jats:sc>\u2010trihydroxyllysine <jats:bold>2<\/jats:bold> was an effective building block for the synthesis of multivalent ligands applicable to medical use.<\/jats:p>","DOI":"10.1002\/asia.200800250","type":"journal-article","created":{"date-parts":[[2008,10,27]],"date-time":"2008-10-27T02:47:42Z","timestamp":1225075662000},"page":"2033-2045","source":"Crossref","is-referenced-by-count":3,"title":["The Synthesis of <scp>D<\/scp>\u2010Trihydroxyllysine\u2010Based Oligopeptides as a Hydrophilic Scaffold and its Application to the Synthesis of Bifunctional Chelating Agents for Use as Bone Tracers"],"prefix":"10.1002","volume":"3","author":[{"given":"Hiroshi","family":"Tanaka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshio","family":"Ando","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsutomu","family":"Abe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,11,21]]},"reference":[{"key":"e_1_2_6_1_2","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1021\/cen-v083n023.p030","volume":"83","author":"Marx V.","year":"2005","journal-title":"Chem. 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